Product Description for Bcl-2-like 8
Rabbit anti Human, Mouse, Rat Bcl-2-like 8 Y208.
Presentation: Purified
Product is tested for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Paraffin Sections, Immunoprecipitation, Western blot / Immunoblot.
Presentation: Purified
Product is tested for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Paraffin Sections, Immunoprecipitation, Western blot / Immunoblot.
Properties for Bcl-2-like 8
| Product Category | Antibodies |
|---|---|
| Quantity | 0.1 ml |
| Synonyms | BAD, BBC6, BCL2L8, Bcl-2-binding component 6, Bcl-2-like protein 8, Bcl-XL/Bcl-2-associated death promoter, Bcl2 antagonist of cell death, Bcl2-L-8, Review 004 |
| Presentation | Purified |
| Reactivity | Hu, Ms, Rt |
| Applications | F, ICC/IF, IP, P, WB |
| Clonality | Monoclonal |
| Clone | Y208 |
| Host | Rabbit |
| Isotype | IgG |
| Shipping to | Not USA/Canada |
| PDF datasheet | View Datasheet |
| Manufacturer | Novus Biologicals Inc. |
Datasheet Extract
| Immunogen |
|
|---|---|
| Antibody type | Ab |
| Application | flow cytometry / FACS analysis, Immunocytochemistry, immunohistochemistry, immunoprecipitation, Western Blot, This antibody is useful for Flow cytometry / FACS analysis, Immunohistochemistry, Immunoprecipitation, Western Blot and Immunocytochemistry , flow cytometry / FACS analysis 1:50, immunohistochemistry 1:100-1:250, immunoprecipitation 1:100, Western Blot 1:2000-1:5000, Immunocytochemistry 1:250-1:500 |
| Background | Bad is a pro-apoptotic member of the Bcl-2 family. Bad will bind preferentially Bcl-xL over Bcl-2 through its partial (9-16 a.a) BH3 domain. Additionally, Bad can reverse the death repressor activity of Bcl-xL but not of Bcl-2. Upon dephosphorylation, activated Bad translocates to the mitochondria and displace Bcl-2 from tBid sequestration to initiate mitochondrial dysfunction. The switching on/off of its phosphorylation by growth/survival factors regulates Bad activity. |
| General Readings |
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| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Format |
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| Specificity |
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| Gene ID | 572 |
| FocusOn and Reviews | |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for Bcl-2-like 8 (6 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| GTX25335 |
Bcl-2-like 8 pSer112/75 |
||||||
 |
1 packs /
€390.00
|
||||||
| GeneTex Inc. | |||||||
| GTX27985 |
Bcl-2-like 8 Control Peptide |
||||||
|
0.1 mg /
€230.00
|
||||||
| GeneTex Inc. | |||||||
| H00000572-P01-10 |
Bcl-2-like 8 |
||||||
|
Human | in vitro transl. |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00000572-P01-25 |
Bcl-2-like 8 |
||||||
|
Human | in vitro transl. |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00000572-Q01-10 |
Bcl-2-like 8 |
||||||
|
Human | in vitro transl. |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00000572-Q01-25 |
Bcl-2-like 8 |
||||||
|
Human | in vitro transl. |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
Positive controls for Bcl-2-like 8 (1 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| NBL1-07900 |
Bad Lysate |
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![Western Blot: Bad Lysate [NBL1-07900] - Western Blot experiments. Left-Control; Right -Over-expression Lysate for BAD.](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/Bad Lysate-Western Blot-NBL1-07900-img0001.jpg) |
0.1 mg /
€370.00
|
||||||
| Novus Biologicals Inc. | |||||||
Recommended Secondary Antibodies for Bcl-2-like 8 (6 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | TRITC | |||||
| Acris Antibodies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
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