AP14456PU-N BLK (N-term) antibody

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0.1 mg / €330.00
Delivery Time: 7-10 working days

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Rabbit anti Human, Mouse BLK

AP14456PU-N

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  • AP14456PU-N

Product Description for BLK

Rabbit anti Human, Mouse BLK.
Properties: (N-term)
Presentation: Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.

Properties for BLK

Product Category Antibodies
Quantity 0.1 mg
Synonyms B lymphocyte kinase, Review 004, Tyrosine-protein kinase BLK, p55-BLK, p55BLK
Presentation Purified
Reactivity Hu, Ms
Applications E, P, WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH

Datasheet Extract

Immunogen
Swiss Prot Num:
P51451
Immunogen:
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human BLK.
Genename:
640
Property N-term
Antibody type Ab
Control peptide AP14456CP-N
Application ELISA: 1/1,000.
Western blotting: 1/100 - 1/500.
Immunohistochemistry: 1/50 - 1/100.
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
Caution This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Concentration 0.25 mg/ml
General Readings
  • Islam, K.B., et al., J. Immunol. 154(3):1265-1272 (1995).
  • Drebin, J.A., et al., Oncogene 10(3):477-486 (1995).
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Buffer System:
PBS with 0.09% (W/V) sodium azide
State:
Liquid purified Ig
Purified
Specificity
Specificity:
This antibody reacts to BLK.
Species:
Human, Mouse.
Gene ID 640
FocusOn and Reviews
Reviews:
Targets

Accessory Products

Proteins and/or Positive Controls

Proteins for BLK (2 products)

Catalog No. Species Pres. Purity   Source  
H00000640-Q01-10

BLK

BLK Human in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00000640-Q01-25

BLK

BLK Human in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.

Positive controls for BLK (1 products)

Catalog No. Species Pres. Purity   Source  
H00000640-T01

BLK 293T Cell Transient Overexpression Lysate(Denatured)

BLK 293T Cell Transient Overexpression Lysate(Denatured)
0.1 ml / €240.00
  Abnova Taiwan Corp.