BP1006 Candida albicans antibody

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1 ml / €360.00
Delivery Time: 10 working days

Quick Overview

Rabbit anti Candida Candida albicans

BP1006

Product Description for Candida albicans

Rabbit anti Candida Candida albicans.
Presentation: Purified
Product is tested for Frozen Sections, Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for Candida albicans

Product Category Antibodies
Quantity 1 ml
Presentation Purified
Reactivity Candida
Applications C, E, ICC/IF, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH

Datasheet Extract

Immunogen
Immunogen:
Candida albicans, type A.
Antibody type Ab
Application Suitable for use in ELISA, IFA, Immunohistochemistry, Double Diffusion and CIE.
Also suitable for conjugation purposes.
Use neat in gel-precipitin reactions.

Background Candida albicans is the most frequently isolated fungal pathogen of Humans, affecting immunocompromised patients ranging from premature infants to AIDS sufferers. Systemic infections have an attributed mortality of 30-50%. C. albicans is a diploid organism which has eight sets of homologous chromosomes. It has a genome of approximately 16 Mb (haploid), about 30% greater than S. cerevisiae (baker's yeast).
Concentration 4-5 mg/ml (OD280 nm, E0.1% = 1.4)
Product Citations
  • Schild L, Heyken A, de Groot PW, Hiller E, Mock M, de Koster C, et al. Proteolytic cleavage of covalently linked cell wall proteins by Candida albicans Sap9 and Sap10. Eukaryot Cell. 2011 Jan;10(1):98-109. doi: 10.1128/EC.00210-10. Epub 2010 Nov 19. PubMed PMID: 21097664.
  • Schild L, Heyken A, de Groot PW, Hiller E, Mock M, de Koster C, et al. Proteolytic cleavage of covalently linked cell wall proteins by Candida albicans Sap9 and Sap10. Eukaryot Cell. 2011 Jan;10(1):98-109. doi: 10.1128/EC.00210-10. Epub 2010 Nov 19. PubMed PMID: 21097664.
General Readings
  • Brand, A., et al., (2008), "An Internal Polarity Landmark is Important for Externally Induced Hyphal Behaviors in Candida albicans", Eukaryotic Cell, 7(4): 712-720.
  • Fratti, R.A., et al., (1998), "Endothelial Cell Injury Caused by Candida albicans Is Dependent on Iron", Infection and Immunity, 66(1): 191-196.
  • Tsuchimori N, Sharkey LL, Fonzi WA, French SW, Edwards JE, Filler SG. Reduced virulence of HWP1-deficient mutants of Candida albicans and their interactions with host cells. Infect Immun. 2000 Apr;68(4):1997-2002. PubMed PMID: 10722594.
  • Phan, Q.T., et al., (2005), "N-cadherin Mediates Endocytosis of Candida albicans by Endothelial Cells", The Journal of Biological Chemistry, 280(11): 10455-10461.
  • Phan, Q.T., et al., (2000), "Role of Hyphal Formation in Interactions of Candida albicans with Endothelial Cells", Infection and Immunity, 68(6): 3485-3490.
  • Martinez-Lopez, R., et al., (2006), "Candida albicans Ecm33p is Important for Normal Cell Wall Architecture and Interactions with Host Cells", Eukaryotic Cell., 5(1): 140-147.
  • Palmer, G.E., et al., (2005), "The Candida albicans Vacuole is Required for Differentiation and Efficient Macrophage Killing", Eukaryotic Cell., 4(10): 1677-1686.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein A Chromatography
Buffer System:
0.01M PBS, pH 7.2 containing 0.09% Sodium Azide as preservative without stabilizing proteins
State:
Liquid purified Ig fraction (>95% pure)
Purified
Specificity
Specificity:
Recognizes numerous proteins in a soluble C. albicans extract (IEP).
Has not been absorbed and does cross-react with other Yeasts.
Negative against Human serum, urine and spinal fluid.
Targets

Accessory Products