DP064 Caspase-1 antibody

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1 ml / €510.00
Delivery Time: 5-7 working days

Quick Overview

Rabbit anti Human, Mouse, Rat Caspase-1

Product Description for Caspase-1

Rabbit anti Human, Mouse, Rat Caspase-1.
Presentation: Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Properties for Caspase-1

Product Category Antibodies
Quantity 1 ml
Synonyms CASP-1, CASP1, FocusOn051, ICE, IL1BC, IL1BCE, Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45
Presentation Purified
Reactivity Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH

Datasheet Extract

Immunogen
Swiss Prot Num:
P29466
Immunogen:
A synthetic peptide from the second quarter of human Caspase 1 protein.
Genename:
834
Antibody type Ab
Application Immunohistochemistry on paraffin embedded sections.
This antibody may be diluted to a titer of 1:25-1:50 in an ABC method. We suggest an incubation period of 30 minutes at room temperature. High temperature treatment of formalin-fixed, paraffin embedded tissue sections with 10mM citrate buffer, pH 6.0 must be performed prior to the immunostaining.
Positive Control: Placenta.
Western Blot.
Background Caspase 1 is expressed as a proenzyme in many tissues. Active Caspase 1 is a tetramer of two subunits p10 and p20 in 2:2 ratio. Overexpression of Caspase 1 can induce apoptosis in fibroblast, which can be inhibited by Overexpression of Crm A, a protein from pox virus.
General Readings Enari et al. Nature 375: 78, 1995.
Walker et al. Cell 78: 343, 1994.
Storage Store the antibody at 2-8°C.
Shelf life: one year from despatch.
Format
State:
Liquid purified immunoglobulin fraction containing sodium azide as preservative.
Purified
Specificity
Specificity:
This antibody reacts with a 45 kD protein, Caspase 1.
Cellular Localization: Nuclear, cell membrane.
Species:
Human, mouse and rat.
Gene ID 834
FocusOn and Reviews
FocusOns:
Targets

Accessory Products

Proteins and/or Positive Controls

Proteins for Caspase-1 (4 products)

Catalog No. Species Pres. Purity   Source  
H00000834-P01-10

Caspase-1

Caspase-1 Human Purified
10 µg / €350.00
  Abnova Taiwan Corp.
H00000834-P01-25

Caspase-1

Caspase-1 Human Purified
25 µg / €500.00
  Abnova Taiwan Corp.
H00000834-Q01-10

Caspase-1

Caspase-1 Human in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00000834-Q01-25

Caspase-1

Caspase-1 Human in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.

Positive controls for Caspase-1 (2 products)

Catalog No. Species Pres. Purity   Source  
NBL1-08705

Caspase 1 Lysate

Western Blot: Caspase 1 Lysate [NBL1-08705] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for CASP1
0.1 mg / €370.00
  Novus Biologicals Inc.
NBL1-08706

Caspase 1 Lysate

Caspase 1 Lysate
0.1 mg / €370.00
  Novus Biologicals Inc.