Product Description for Caspase-1
Rabbit anti Human, Mouse, Rat Caspase-1.
Presentation: Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.
Presentation: Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.
Properties for Caspase-1
| Product Category | Antibodies |
|---|---|
| Quantity | 1 ml |
| Synonyms | CASP-1, CASP1, FocusOn051, ICE, IL1BC, IL1BCE, Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45 |
| Presentation | Purified |
| Reactivity | Hu, Ms, Rt |
| Applications | P, WB |
| Clonality | Polyclonal |
| Host | Rabbit |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | Acris Antibodies GmbH |
Datasheet Extract
| Immunogen |
|
|---|---|
| Antibody type | Ab |
| Application | Immunohistochemistry on paraffin embedded sections. This antibody may be diluted to a titer of 1:25-1:50 in an ABC method. We suggest an incubation period of 30 minutes at room temperature. High temperature treatment of formalin-fixed, paraffin embedded tissue sections with 10mM citrate buffer, pH 6.0 must be performed prior to the immunostaining. Positive Control: Placenta. Western Blot. |
| Background | Caspase 1 is expressed as a proenzyme in many tissues. Active Caspase 1 is a tetramer of two subunits p10 and p20 in 2:2 ratio. Overexpression of Caspase 1 can induce apoptosis in fibroblast, which can be inhibited by Overexpression of Crm A, a protein from pox virus. |
| General Readings | Enari et al. Nature 375: 78, 1995. Walker et al. Cell 78: 343, 1994. |
| Storage | Store the antibody at 2-8°C. Shelf life: one year from despatch. |
| Format |
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| Specificity |
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| Gene ID | 834 |
| FocusOn and Reviews | |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for Caspase-1 (4 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00000834-P01-10 |
Caspase-1 |
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Human | Purified |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00000834-P01-25 |
Caspase-1 |
||||||
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Human | Purified |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00000834-Q01-10 |
Caspase-1 |
||||||
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Human | in vitro transl. |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00000834-Q01-25 |
Caspase-1 |
||||||
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Human | in vitro transl. |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
Positive controls for Caspase-1 (2 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| NBL1-08705 |
Caspase 1 Lysate |
||||||
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0.1 mg /
€370.00
|
||||||
| Novus Biologicals Inc. | |||||||
| NBL1-08706 |
Caspase 1 Lysate |
||||||
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0.1 mg /
€370.00
|
||||||
| Novus Biologicals Inc. | |||||||
Recommended Secondary Antibodies for Caspase-1 (6 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | TRITC | |||||
| Acris Antibodies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||


![Western Blot: Caspase 1 Lysate [NBL1-08705] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for CASP1](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/Caspase 1 Lysate-Western Blot-NBL1-08705-img0001.jpg)




