AP20058PU-N CD107b / LAMP2 (C-term) antibody

Swiss Prot Num:

P13473

Immunogen:

LAMP2 antibody was raised against a 17 amino acid peptide from near the carboxy of Human LAMP-2 (NP_054701).

Genename:

3920

• Gozuacik D, Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene. 2004 Apr 12;23(16):2891-906. PubMed PMID: 15077152.
• Kisen GO, Tessitore L, Costelli P, Gordon PB, Schwarze PE, Baccino FM, et al. Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells. Carcinogenesis. 1993 Dec;14(12):2501-5. PubMed PMID: 8269618.
• Kamada Y, Funakoshi T, Shintani T, et al. Tor-mediated induction of autophagy via Apg1 protein kinase complex. J. Cell. Biol. 2000; 150:1507-13.
• Granger BL, Green SA, Gabel CA, et al. Characterization and cloning of the lgp110, a lysosomal glycoprotein from mouse and rat cells. J. Biol. Chem. 1990; 265:12036-43.
• Tanaka Y, Guhde G, Suter A, et al. Accumulation of autophagic vacuoles and cardiopathy in LAMP-2-deficient mice. Nature 2000; 902-6.
• Nishino I, Fu J, Tanji K, Yamada T, Shimojo S, Koori T, et al. Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease). Nature. 2000 Aug 24;406(6798):906-10. PubMed PMID: 10972294.
• Gough NR, Hatem CL, Fambrough DM. The family of LAMP-2 proteins arises by alternative splicing from a single gene: characterization of the avian LAMP-2 gene and identification of mammalian homologs of LAMP-2b and LAMP-2c. DNA Cell Biol. 1995 Oct;14(10):863-7. PubMed PMID: 7546292.

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Purification:

Immunoaffinity Chromatography

Buffer System:

PBS containing 0.02% Sodium Azide as preservative

State:

Liquid purified Ig fraction
Aff - Purified

Species reactivity (tested):

Human, Mouse.

Specificity:

Recognizes CD107b/LAMP2 (C-term).