CD196 / CCR6 (N-term) - AM03124PU-S

Product Description for CD196 / CCR6

Mouse anti Human CD196 / CCR6 4C6.
Properties: (N-term)
Presentation: Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for CD196 / CCR6

Product Category	Antibodies
Quantity	50 µl
Synonyms	C-C CKR-6, C-C chemokine receptor type 6, CC-CKR-6, CCR-6, CKRL3, CMKBR6, Chemokine receptor-like 3, DRY6, FocusOn007, G-protein coupled receptor 29, GPR-CY4, GPR29, LARC receptor, STRL22
Presentation	Purified
Reactivity	Hu
Applications	E, WB
Clonality	Monoclonal
Clone	4C6
Host	Mouse
Isotype	IgG1
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	Acris Antibodies GmbH

Datasheet Extract

Immunogen	Swiss Prot Num: P51684 Immunogen: Recombinant human CCR6 (1-46aa) Genename: 1235
Property	N-term
Antibody type	Ab
Application	ELISA. Western blot (1:500 - 1:1,000).
Background	CCR6 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. CCR6 has been reported to be expressed in intestine, colon, liver, lymph node, spleen, lung, blood, umbilical cord, placenta, skin, and pancreas. It has also been reported to be expressed in lymphocytes, T cells, and B cells.
Concentration	1.0 mg/ml
General Readings	Singh SP, et al. (2008) J Immunol. 180(1):214-21. Wen H, et al. (2007) Eur J Immunol. 37(9):2487-89.
Storage	Store the antibody at 2-8°C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Format	Purification: Protein-G affinity chromatography Buffer System: PBS, pH 7.4, containing 0.09 % Sodium Azide State: Liquid purified Ig fraction Purified
Specificity	Specificity: This antibody detects human CCR6. Other species not tested. Species: Human
Gene ID	1235
FocusOn and Reviews	FocusOns: Antibody Panel to Chemokine Receptor Family - FocusOn 007
Targets	CD196 / CCR6 antibody

Accessory Products

Proteins and/or Positive Controls

Proteins for CD196 / CCR6 (1 products)

Catalog No.	Species
H00001235-G01	CD196 / CCR6
	Human	2 µg / €400.00
		Abnova Taiwan Corp.

Positive controls for CD196 / CCR6 (3 products)

Catalog No.	Species
H00001235-T01	CCR6 293T Cell Transient Overexpression Lysate(Denatured)
		0.1 ml / €240.00
		Abnova Taiwan Corp.
NBL1-08893	CCR6 Lysate
		0.1 mg / €370.00
		Novus Biologicals Inc.
NBL1-08894	CCR6 Lysate
		0.1 mg / €370.00
		Novus Biologicals Inc.

Recommended Secondary Antibodies for CD196 / CCR6 (8 products)

Catalog No.	Host	Pres.
R1253AP	Mouse IgG (H+L chain) antibody
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R1253B	Mouse IgG (H+L chain) antibody
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R1253F	Mouse IgG (H+L chain) antibody
	Rabbit	FITC
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R1253HRP	Mouse IgG (H+L chain) antibody
	Rabbit	HRP
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R1253TR	Mouse IgG (H+L chain) antibody
	Rabbit	Texas Red
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R1403R	Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
	Rabbit	PE
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R1405R	Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
	Goat	PE
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R1455R	Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
	Donkey	PE
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