CD273 / PDL2

Product Description for CD273 / PDL2

Mouse anti Human CD273 / PDL2 MIH14.
Presentation: PE
Product is tested for Flow Cytometry.

Properties for CD273 / PDL2

Product Category	Antibodies
Quantity	100 Tests
Synonyms	B7DC, FocusOn019, PD-1-ligand 2, PD-L2, PDCD1 ligand 2, PDCD1L2, PDCD1LG2, Programmed cell death 1 ligand 2, Programmed death ligand 2
Presentation	PE
Reactivity	Hu
Applications	F
Clonality	Monoclonal
Clone	MIH14
Host	Mouse
Isotype	IgG1
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	Acris Antibodies GmbH

Datasheet Extract

Immunogen	Swiss Prot Num: Q9BQ51 Immunogen: Human B7-DC transfected L cells Genename: 80380
Antibody type	Ab
Application	Flow Cytometry.
Background	CD273 functions to inhibit T-cell proliferation by blocking cell cycle progression and cytokine production, and is particularly important in the maintenance of self tolerance.
Concentration	0.1 mg/ml
General Readings	Konishi J, Yamazaki K, Azuma M, Kinoshita I, Dosaka-Akita H, Nishimura M. B7-H1 expression on non-small cell lung cancer cells and its relationship with tumor-infiltrating lymphocytes and their PD-1 expression. Clin Cancer Res. 2004 Aug 1;10(15):5094-100. PubMed PMID: 15297412.
Storage	Prior to and following reconstitution store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch.
Format	Label: R. Phycoerythrin (RPE) PE Purification: Affinity chromatography on Protein G Buffer System: Phosphate buffered saline pH 7.4, 0.09% Sodium Azide (NaN3), 1% Bovine Serum Albumin Purity: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant State: Lyophilised Ig fraction Reconstitution: Reconstitute with 1.0ml distilled water
Specificity	Specificity: This antibody detects CD273, also known as B7-DC and Programmed Death Ligand 2 (PD-L2). CD273 is a 42kD member of the immunoglobulin receptor superfamily, and is a ligand for CD279 (PD-1). CD273 is primarily expressed on dendritic cells, and its expression can be induced on inflammatory macrophages when activated by interleukin 4 or Th2 cells. Species: Human.
Gene ID	80380
FocusOn and Reviews	FocusOns: Antibodies to Programmed Death-1 (PD-1) and its Ligands PD-L1 and PD-L2 - FocusOn 019
Targets	CD273 / PDL2 antibody

Accessory Products

Proteins and/or Positive Controls

Proteins for CD273 / PDL2 (2 products)

Catalog No.	Species	Pres.
H00080380-Q01-10	CD273 / PDL2
	Human	Purified	10 µg / €350.00
			Abnova Taiwan Corp.
H00080380-Q01-25	CD273 / PDL2
	Human	Purified	25 µg / €500.00
			Abnova Taiwan Corp.

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