Product Description for CD284 / TLR4
Mouse anti Bovine, Chimpanzee, Equine, Human, Mouse, Porcine, Rat, Sheep CD284 / TLR4 76B357.1.
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot, Flow Cytometry, Paraffin Sections.
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot, Flow Cytometry, Paraffin Sections.
Properties for CD284 / TLR4
| Product Category | Antibodies |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | FocusOn004, Toll-like receptor 4 |
| Presentation | Purified |
| Reactivity | Bov, Chimp, Eq, Hu, Ms, Por, Rt, Sh |
| Applications | F, ICC/IF, P, WB |
| Clonality | Monoclonal |
| Clone | 76B357.1 |
| Host | Mouse |
| Isotype | IgG2b |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | Acris Antibodies GmbH |
Datasheet Extract
| Immunogen |
|
|---|---|
| Antibody type | Ab |
| Application | Flow Cytometry (cell surface): 0.5-2 µg/10e6 cells. Recommended Positive Control: ThP1, Ramos. Flow Cytometry (Intracellular): See Cohen et al., 2008 for details. Immunofluorescence: See Nowicki et al, 2009 for details. Western blot: 1-3 µg/ml. Recommended Positive Control: Intestine lysate. Immunohistochemistry on Paraffin Sections: 5 µg/ml. |
| Background | Toll like receptors (TLR) are highly conserved throughout evolution and have been implicated in the innate defense to many pathogens. In Drosophila toll is required for the anti fungal response, while the related 18 wheeler is involved in antibacterial defenses. In mammals, TLR identified as type I transmembrane signaling receptors with pattern recognition capabilities have been implicated in the innate host defense to pathogens. TLR4 has been identified next to MD2 and CD14 as a receptor that is central to the innate immune response to lipopolysaccharides (LPS) of Gram negative bacteria. TLR4 contributes to the initiation of CNS neuroimmune activation after nerve transection. TLR4 is part of an early, specific, innate CNS/microglial response and maybe relevant in the prevention and treatment of neuropathic pain syndromes. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS. |
| Concentration | 0.5 mg/ml |
| General Readings |
|
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Format |
|
| Species Reactivity |
|
| Specificity |
|
| FocusOn and Reviews | |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for CD284 / TLR4 (8 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00007099-G01 |
CD284 / TLR4 |
||||||
 |
Human |
10 µg /
€530.00
|
|||||
| Abnova Taiwan Corp. | |||||||
| H00007099-P01-10 |
CD284 / TLR4 |
||||||
|
Human | Purified |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00007099-P01-25 |
CD284 / TLR4 |
||||||
|
Human | Purified |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00007099-Q01-10 |
CD284 / TLR4 |
||||||
|
Human | in vitro transl. |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00007099-Q01-25 |
CD284 / TLR4 |
||||||
|
Human | in vitro transl. |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00007099-Q02 |
CD284 / TLR4 |
||||||
|
Human | Purified |
10 µg /
€330.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00007099-Q02-10 |
CD284 / TLR4 |
||||||
|
Human | Purified |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00007099-Q02-25 |
CD284 / TLR4 |
||||||
|
Human | Purified |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
Positive controls for CD284 / TLR4 (1 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00007099-T01 |
CD284 / TLR4 |
||||||
|
0.1 ml /
€240.00
|
||||||
| Abnova Taiwan Corp. | |||||||
Recommended Secondary Antibodies for CD284 / TLR4 (8 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1253AP |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1253B |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1253F |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1253HRP |
Mouse IgG (H+L chain) antibody |
||||||
|
Rabbit | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1253TR |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Texas Red | |||||
| Acris Antibodies GmbH | |||||||
| R1403R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Rabbit | PE | |||||
| Acris Antibodies GmbH | |||||||
| R1405R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Goat | PE | |||||
| Acris Antibodies GmbH | |||||||
| R1455R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
Compare Products
You have no items to compare.
My Cart
You have no items in your shopping cart.
Antibody Location Service
Over 230,000 products but you can't find the right antibody for your protein or application?
Acris will do the search for you!
