SM7105AF488 CD289 / TLR9 (Isoform A, 268-284) antibody

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0.1 mg / €390.00
Delivery Time: 5-7 working days

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Mouse anti Canine, Equine, Human, Monkey, Mouse, Rat CD289 / TLR9 26C593.2

Product Description for CD289 / TLR9

Mouse anti Canine, Equine, Human, Monkey, Mouse, Rat CD289 / TLR9 26C593.2.
Properties: (Isoform A, 268-284)
Presentation: Alexa Fluor 488
Product is tested for Immunocytochemistry/Immunofluorescence, Flow Cytometry.

Properties for CD289 / TLR9

Product Category Antibodies
Quantity 0.1 mg
Synonyms FocusOn004, Toll-like receptor 9, UNQ5798/PRO19605
Presentation Alexa Fluor 488
Reactivity Can, Eq, Hu, Mky, Ms, Rt
Applications F, ICC/IF
Clonality Monoclonal
Clone 26C593.2
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9NR96
Immunogen:
KLH-conjugated synthetic peptide corresponding to amino acids 268-284 of human TLR9 isoform A
AA Sequence:
CPRHFPQLHPDTFSHLS
Genename:
54106
Property 268-284, Isoform A
Antibody type Ab
Application Flow cytometry (Intracellular): 0.5-1.0 µg/10e6 cells
Flow cytometry (Cell surface.
Immunoflourescence/Immunocytochemistry.
Confocal microscopy.
Background The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). Ten human homologs of TLRs (TLR1-10) have been described (3). By using a BLAST search, Hemmi et al., 2000 (5) have identified and subsequently isolated a cDNA coding for TLR9. Gene knockout experiments suggest that TLR9 acts as a receptor for unmethylated CpG dinucleotides in the bacterial DNA (4). Human and mouse TLR9 share an overall amino-acid identity of 75.5%. TLR9 is highly expressed in spleen.
Concentration 0.5 mg/ml
General Readings
  • Muzio M, Natoli G, Saccani S, Levrero M, and Mantovani A. J. exp. Med. 187: 2097-2101 (1998).
  • Medzhitov R and Janeway CA. Cell 91: 295-298 (1997).
  • Chuang TH and Ulevitch RJ. Biochim. Biophys. Acta 1518 (1-2):157-161 (2001)
  • Takeuchi O, Kawai T, Sanjo H, Copeland NG, Gilbert DJ, Jenkins NA, Takeda K, and Akira S. Gene 231: 59-65 (1999).
  • Hemmi H, Takeuchi O, Kawai T, Kaisho T, Sato S, Sanjo H, Matsumoto M, Hoshino K, Wagner H, Takeda K, and Shizo A. Nature 408: 740-745 (2000).
Storage Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf life: six months from despatch
Format
Label:
Alexa Fluor® 488
Alexa Fluor 488
Purification:
Protein G chromatography
Buffer System:
PBS containing 0.05% BSA and 0.05% sodium azide
State:
Liquid Ig fraction
Species Reactivity
Species reactivity (tested):
Dog, Horse, Human, Mouse, Rat, Rhesus Monkey
Specificity
Specificity:
This antibody detects CD289 / TLR9, Isoform A.
Gene ID 54106
FocusOn and Reviews
FocusOns:
Targets

Accessory Products

Proteins and/or Positive Controls

Proteins for CD289 / TLR9 (1 products)

Catalog No. Species Pres. Purity   Source  
H00054106-G01

CD289 / TLR9

CD289 / TLR9 Human
10 µg / €530.00
  Abnova Taiwan Corp.

Positive controls for CD289 / TLR9 (1 products)

Catalog No. Species Pres. Purity   Source  
NBL1-16957

TLR9 Lysate

Western Blot: TLR9 Lysate [NBL1-16957] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for TLR9
0.1 mg / €370.00
  Novus Biologicals Inc.