Product Description for CD289 / TLR9
Mouse anti Canine, Equine, Human, Monkey, Mouse, Rat CD289 / TLR9 26C593.2.
Properties: (268-284)
Presentation: PE
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Paraffin Sections, Flow Cytometry.
Properties: (268-284)
Presentation: PE
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Paraffin Sections, Flow Cytometry.
Properties for CD289 / TLR9
| Product Category | Antibodies |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | FocusOn004, Toll-like receptor 9, UNQ5798/PRO19605 |
| Presentation | PE |
| Reactivity | Can, Eq, Hu, Mky, Ms, Rt |
| Applications | C, F, ICC/IF, P |
| Clonality | Monoclonal |
| Clone | 26C593.2 |
| Host | Mouse |
| Isotype | IgG1 |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | Acris Antibodies GmbH |
Datasheet Extract
| Immunogen |
|
|---|---|
| Property | 268-284 |
| Antibody type | Ab |
| Application | Confocal Microscopy: See Greene et. al. (2005). Flow Cytometry (Intracellular): 0.1-0.5 µg/1x10e6 cells. Flow Cytometry (Cell surface): See Greene et. al. (2005). Immunohistochemistry on Frozen Sections: 10-20 µg/ml (See Miller et al, 2005). Immunohistochemistry on Paraffin Sections: See Miller et al, 2005. Recommended Positive Control: Ramos, Human PBMCs. |
| Background | The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). Ten human homologs of TLRs (TLR1-10) have been described (3). By using a BLAST search, Hemmi et al., 2000 (4) have identified and subsequently isolated a cDNA coding for TLR9. Gene knockout experiments suggest that TLR9 acts as a receptor for unmethylated CpG dinucleotides in the bacterial DNA (4). Human and mouse TLR9 share an overall amino-acid identity of 75.5%. TLR9 is highly expressed in spleen. |
| Concentration | 0.5 mg/ml |
| General Readings |
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| Storage | Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch. |
| Format |
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| Species Reactivity |
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| Specificity |
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| Gene ID | 54106 |
| FocusOn and Reviews | |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for CD289 / TLR9 (1 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00054106-G01 |
CD289 / TLR9 |
||||||
 |
Human |
10 µg /
€530.00
|
|||||
| Abnova Taiwan Corp. | |||||||
Positive controls for CD289 / TLR9 (1 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| NBL1-16957 |
TLR9 Lysate |
||||||
![Western Blot: TLR9 Lysate [NBL1-16957] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for TLR9](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/TLR9 Lysate-Western Blot-NBL1-16957-img0001.jpg) |
0.1 mg /
€370.00
|
||||||
| Novus Biologicals Inc. | |||||||
Recommended Secondary Antibodies for CD289 / TLR9 (8 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1253AP |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1253B |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1253F |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1253HRP |
Mouse IgG (H+L chain) antibody |
||||||
|
Rabbit | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1253TR |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Texas Red | |||||
| Acris Antibodies GmbH | |||||||
| R1403R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Rabbit | PE | |||||
| Acris Antibodies GmbH | |||||||
| R1405R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Goat | PE | |||||
| Acris Antibodies GmbH | |||||||
| R1455R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
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