Product Description for CD309 / VEGFR-2 / Flk-1
Mouse anti Human CD309 / VEGFR-2 / Flk-1 4H3.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot, Flow Cytometry.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot, Flow Cytometry.
Properties for CD309 / VEGFR-2 / Flk-1
| Product Category | Antibodies |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | FLK1, FocusOn005, KDR, Kinase NYK, Kinase insert domain receptor, Protein-tyrosine kinase receptor Flk-1, VEGF Receptor 2, VEGFR2, Vascular endothelial growth factor receptor 2 |
| Presentation | Purified |
| Reactivity | Hu |
| Applications | E, F, WB |
| Clonality | Monoclonal |
| Clone | 4H3 |
| Host | Mouse |
| Isotype | IgG1 |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | Acris Antibodies GmbH |
Datasheet Extract
| Immunogen |
|
|---|---|
| Antibody type | Ab |
| Application | ELISA: 1-15 µg/ml. Western blotting: 1-2 µg/ml. Flow Cytometry Analysis and Cell Sorting: Use at 2-5 µg/ml together with the appropriate secondary reagents. |
| Background | VEGF receptor 2 is a member of a receptor tyrosine kinase family whose activation plays an essential role in a large number of biological processes such as embryonic development, wound healing, cell proliferation, migration and differentiation. Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues. These sites can be involved in the regulation of kinase activity or serve as binding sites for SH2 and phosphotyrosine binding containing signalling proteins. Phosphorylation of Tyrosines 1054 and 1059 in the activation loop is required for activation of VEGF receptor 2 and its intrinsic tyrosine kinase activity. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. |
| General Readings |
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| Storage | The lyophilized antibody, thought stable at room temperature, is best stored desiccated below 0°C. Shelf life: one year from despatch. Reconstituted anti-VEGFR-2/KDR is stable at 2-8°C for one month or can be stored in working aliquots at -20°C for six months. Avoid repeated freezing and thawing. |
| Format |
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| Species Reactivity |
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| Specificity |
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| Gene ID | 3791 |
| FocusOn and Reviews | |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for CD309 / VEGFR-2 / Flk-1 (8 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| AR26018PU-L |
CD309 / VEGFR-2 / Flk-1 (esKDR) |
||||||
 |
Human | Purified | > 95 % | Insect cells |
20 µg /
€430.00
|
||
| Acris Antibodies GmbH | |||||||
| AR26018PU-N |
CD309 / VEGFR-2 / Flk-1 (esKDR) |
||||||
|
Human | Purified | > 95 % | Insect cells |
5 µg /
€210.00
|
||
| Acris Antibodies GmbH | |||||||
| DA3530 |
CD309 / VEGFR-2 / Flk-1 (D1-D7) |
||||||
 |
Human | Purified | > 95 % | Insect cells |
5 µg /
€130.00
|
||
| Acris Antibodies GmbH | |||||||
| DA3530X |
CD309 / VEGFR-2 / Flk-1 (D1-D7) |
||||||
|
Human | Purified | > 90 % | Insect cells |
50 µg /
€360.00
|
||
| Acris Antibodies GmbH | |||||||
| DA3531 |
CD309 / VEGFR-2 / Flk-1 (D1-7) (Fc Chimera) |
||||||
|
Human | Purified | > 90 % | Insect cells |
50 µg /
€280.00
|
||
| Acris Antibodies GmbH | |||||||
| DA3531S |
CD309 / VEGFR-2 / Flk-1 (D1-7) (Fc Chimera) |
||||||
|
Human | Purified | > 90 % | Insect cells |
10 µg /
€150.00
|
||
| Acris Antibodies GmbH | |||||||
| H00003791-Q01-10 |
CD309 / VEGFR-2 / Flk-1 |
||||||
|
Human | in vitro transl. |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00003791-Q01-25 |
CD309 / VEGFR-2 / Flk-1 |
||||||
|
Human | in vitro transl. |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
Positive controls for CD309 / VEGFR-2 / Flk-1 (1 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| NBL1-06701 |
VEGF Receptor 2 Lysate |
||||||
![Western Blot: VEGFR1/VEGFR2 Antibody [NB100-527] - Western Blot on VEGFR2 overexpression lysates.](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/NBL1-06701.jpg) |
0.1 ml /
€170.00
|
||||||
| Novus Biologicals Inc. | |||||||
Recommended Secondary Antibodies for CD309 / VEGFR-2 / Flk-1 (8 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1253AP |
Mouse IgG (H+L chain) antibody |
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|
|
Rabbit | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1253B |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1253F |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1253HRP |
Mouse IgG (H+L chain) antibody |
||||||
|
Rabbit | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1253TR |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Texas Red | |||||
| Acris Antibodies GmbH | |||||||
| R1403R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Rabbit | PE | |||||
| Acris Antibodies GmbH | |||||||
| R1405R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Goat | PE | |||||
| Acris Antibodies GmbH | |||||||
| R1455R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
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