Product Description for CD309 / VEGFR-2 / Flk-1
Rabbit anti Human, Mouse, Rat CD309 / VEGFR-2 / Flk-1.
Presentation: Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.
Presentation: Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.
Properties for CD309 / VEGFR-2 / Flk-1
| Product Category | Antibodies |
|---|---|
| Quantity | 0.5 ml |
| Synonyms | FLK1, FocusOn005, KDR, Kinase NYK, Kinase insert domain receptor, Protein-tyrosine kinase receptor Flk-1, VEGF Receptor 2, VEGFR2, Vascular endothelial growth factor receptor 2 |
| Presentation | Purified |
| Reactivity | Hu, Ms, Rt |
| Applications | P, WB |
| Clonality | Polyclonal |
| Host | Rabbit |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | Acris Antibodies GmbH |
Datasheet Extract
| Immunogen |
|
|---|---|
| Antibody type | Ab |
| Application | Western Blotting. Immunohistochemistry on Paraffin Sections: Use a 1/50-1/100 dilution in an ABC method (incubation time: 30 minutes at room temperature). Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Recommended positive control: Angiosarcoma. |
| Background | CD309 is a member of a receptor tyrosine kinase family whose activation plays an essential role in a large number of biological processes such as embryonic development, wound healing, cell proliferation, migration and differentiation. Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues. These sites can be involved in the regulation of kinase activity or serve as binding sites for SH2 and phosphotyrosine binding containing signalling proteins. Phosphorylation of Tyrosines 1054 and 1059 in the activation loop is required for activation of VEGF receptor 2 and its intrinsic tyrosine kinase activity. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. |
| General Readings |
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| Storage | Store the antibody undiluted at 2-8°C. Shelf life: one year from despatch. |
| Format |
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| Specificity |
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| Gene ID | 3791 |
| FocusOn and Reviews | |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for CD309 / VEGFR-2 / Flk-1 (8 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| AR26018PU-L |
CD309 / VEGFR-2 / Flk-1 (esKDR) |
||||||
 |
Human | Purified | > 95 % | Insect cells |
20 µg /
€430.00
|
||
| Acris Antibodies GmbH | |||||||
| AR26018PU-N |
CD309 / VEGFR-2 / Flk-1 (esKDR) |
||||||
|
Human | Purified | > 95 % | Insect cells |
5 µg /
€210.00
|
||
| Acris Antibodies GmbH | |||||||
| DA3530 |
CD309 / VEGFR-2 / Flk-1 (D1-D7) |
||||||
 |
Human | Purified | > 95 % | Insect cells |
5 µg /
€130.00
|
||
| Acris Antibodies GmbH | |||||||
| DA3530X |
CD309 / VEGFR-2 / Flk-1 (D1-D7) |
||||||
|
Human | Purified | > 90 % | Insect cells |
50 µg /
€360.00
|
||
| Acris Antibodies GmbH | |||||||
| DA3531 |
CD309 / VEGFR-2 / Flk-1 (D1-7) (Fc Chimera) |
||||||
|
Human | Purified | > 90 % | Insect cells |
50 µg /
€280.00
|
||
| Acris Antibodies GmbH | |||||||
| DA3531S |
CD309 / VEGFR-2 / Flk-1 (D1-7) (Fc Chimera) |
||||||
|
Human | Purified | > 90 % | Insect cells |
10 µg /
€150.00
|
||
| Acris Antibodies GmbH | |||||||
| H00003791-Q01-10 |
CD309 / VEGFR-2 / Flk-1 |
||||||
|
Human | in vitro transl. |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00003791-Q01-25 |
CD309 / VEGFR-2 / Flk-1 |
||||||
|
Human | in vitro transl. |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
Positive controls for CD309 / VEGFR-2 / Flk-1 (1 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| NBL1-06701 |
VEGF Receptor 2 Lysate |
||||||
![Western Blot: VEGFR1/VEGFR2 Antibody [NB100-527] - Western Blot on VEGFR2 overexpression lysates.](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/NBL1-06701.jpg) |
0.1 ml /
€170.00
|
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| Novus Biologicals Inc. | |||||||
Recommended Secondary Antibodies for CD309 / VEGFR-2 / Flk-1 (6 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | TRITC | |||||
| Acris Antibodies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
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