Product Description for CD309 / VEGFR-2 / Flk-1
Rabbit anti Human CD309 / VEGFR-2 / Flk-1.
Presentation: Azide Free
Product is tested for Frozen Sections, Enzyme Immunoassay, Functional assay, Immunoprecipitation, Western blot / Immunoblot.
Presentation: Azide Free
Product is tested for Frozen Sections, Enzyme Immunoassay, Functional assay, Immunoprecipitation, Western blot / Immunoblot.
Properties for CD309 / VEGFR-2 / Flk-1
| Product Category | Antibodies |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | FLK1, FocusOn005, KDR, Kinase NYK, Kinase insert domain receptor, Protein-tyrosine kinase receptor Flk-1, VEGF Receptor 2, VEGFR2, Vascular endothelial growth factor receptor 2 |
| Presentation | Azide Free |
| Reactivity | Hu |
| Applications | C, E, FN, IP, WB |
| Clonality | Polyclonal |
| Host | Rabbit |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | Acris Antibodies GmbH |
Datasheet Extract
| Immunogen |
|
|---|---|
| Antibody type | Ab |
| Application | ELISA (5-15 µg/ml). Western blotting (10-20 µg/ml). Immunoprecipitation (Use 1-2 µg/mg protein lysate). Neutralizing experiments: Depending on the conditions and ligand concentration start with 25-50 µg/ml. Immunohistochemistry with Cryo Sections. |
| Background | VEGF receptor 2 is a member of a receptor tyrosine kinase family whose activation plays an essential role in a large number of biological processes such as embryonic development, wound healing, cell proliferation, migration and differentiation. Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues. These sites can be involved in the regulation of kinase activity or serve as binding sites for SH2 and phosphotyrosine binding containing signalling proteins. Phosphorylation of Tyrosines 1054 and 1059 in the activation loop is required for activation of VEGF receptor 2 and its intrinsic tyrosine kinase activity. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. |
| General Readings |
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| Storage | The lyophilized antibody, thought stable at room temperature, is best stored desiccated below 0°C. Reconstituted anti-VEGFR-2/KDR is stable at 2-8°C for one month or can be stored in working aliquots at -20°C for more than six months. Avoid repeated freezing and thawing. Shelf life: One year from despatch. |
| Format |
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| Species Reactivity |
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| Specificity |
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| Gene ID | 3791 |
| FocusOn and Reviews | |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for CD309 / VEGFR-2 / Flk-1 (8 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| AR26018PU-L |
CD309 / VEGFR-2 / Flk-1 (esKDR) |
||||||
 |
Human | Purified | > 95 % | Insect cells |
20 µg /
€430.00
|
||
| Acris Antibodies GmbH | |||||||
| AR26018PU-N |
CD309 / VEGFR-2 / Flk-1 (esKDR) |
||||||
|
Human | Purified | > 95 % | Insect cells |
5 µg /
€210.00
|
||
| Acris Antibodies GmbH | |||||||
| DA3530 |
CD309 / VEGFR-2 / Flk-1 (D1-D7) |
||||||
 |
Human | Purified | > 95 % | Insect cells |
5 µg /
€130.00
|
||
| Acris Antibodies GmbH | |||||||
| DA3530X |
CD309 / VEGFR-2 / Flk-1 (D1-D7) |
||||||
|
Human | Purified | > 90 % | Insect cells |
50 µg /
€360.00
|
||
| Acris Antibodies GmbH | |||||||
| DA3531 |
CD309 / VEGFR-2 / Flk-1 (D1-7) (Fc Chimera) |
||||||
|
Human | Purified | > 90 % | Insect cells |
50 µg /
€280.00
|
||
| Acris Antibodies GmbH | |||||||
| DA3531S |
CD309 / VEGFR-2 / Flk-1 (D1-7) (Fc Chimera) |
||||||
|
Human | Purified | > 90 % | Insect cells |
10 µg /
€150.00
|
||
| Acris Antibodies GmbH | |||||||
| H00003791-Q01-10 |
CD309 / VEGFR-2 / Flk-1 |
||||||
|
Human | in vitro transl. |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00003791-Q01-25 |
CD309 / VEGFR-2 / Flk-1 |
||||||
|
Human | in vitro transl. |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
Positive controls for CD309 / VEGFR-2 / Flk-1 (1 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| NBL1-06701 |
VEGF Receptor 2 Lysate |
||||||
![Western Blot: VEGFR1/VEGFR2 Antibody [NB100-527] - Western Blot on VEGFR2 overexpression lysates.](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/NBL1-06701.jpg) |
0.1 ml /
€170.00
|
||||||
| Novus Biologicals Inc. | |||||||
Recommended Secondary Antibodies for CD309 / VEGFR-2 / Flk-1 (6 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | TRITC | |||||
| Acris Antibodies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
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