Product Description for CDw198 / CCR8
Rabbit anti Human, Mouse CDw198 / CCR8.
Presentation: Aff - Purified
Product is tested for Paraffin Sections.
Presentation: Aff - Purified
Product is tested for Paraffin Sections.
Properties for CDw198 / CCR8
| Product Category | Antibodies |
|---|---|
| Quantity | 50 µg |
| Synonyms | C-C CKR-8, C-C chemokine receptor type 8, CC-CKR-8, CC-chemokine receptor CHEMR1, CCR-8, CKRL1, CMKBR8, CMKBRL2, Chemokine receptor-like 1, FocusOn007, GPR-CY6, TER1 |
| Presentation | Aff - Purified |
| Reactivity | Hu, Ms |
| Applications | P |
| Clonality | Polyclonal |
| Host | Rabbit |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | Acris Antibodies GmbH |
Datasheet Extract
| Immunogen |
|
|---|---|
| Antibody type | Ab |
| Application | Immunohistochemistry on paraffin embedded sections: 22 µg/ml. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. |
| Background | CCR8 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation regulated cytokine (TARC) and macrophage inflammatory protein 1 beta (MIP1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. CCR8 expression has been reported in spleen and thymus, natural killer cells, monocytes, and T cells, and at lower levels in peripheral blood leukocytes. CCR8 is also believed to be alternative coreceptor with CD4 for HIV-1 infection. |
| Concentration | 1 mg/ml |
| Storage | Store the antibody at 2-8°C for up to one month or at -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Format |
|
| Specificity |
|
| Gene ID | 1237 |
| FocusOn and Reviews | |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for CDw198 / CCR8 (3 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| GTX28123 |
CDw198 / CCR8 |
||||||
 |
50 µg /
€230.00
|
||||||
| GeneTex Inc. | |||||||
| H00001237-G01 |
CDw198 / CCR8 |
||||||
|
Human |
2 µg /
€400.00
|
|||||
| Abnova Taiwan Corp. | |||||||
| H00001237-P01 |
CDw198 / CCR8 |
||||||
|
Human | Purified |
2 µg /
€250.00
|
||||
| Abnova Taiwan Corp. | |||||||
Recommended Secondary Antibodies for CDw198 / CCR8 (6 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | TRITC | |||||
| Acris Antibodies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
Compare Products
You have no items to compare.
My Cart
You have no items in your shopping cart.
Antibody Location Service
Over 230,000 products but you can't find the right antibody for your protein or application?
Acris will do the search for you!
