Cytokeratin 13 (+ KRT10) - DM056-05

Product Description for Cytokeratin 13

Mouse anti Feline, Human, Rat Cytokeratin 13 DE-K13.
Properties: (+ KRT10)
Presentation: Supernatant
Product is tested for Frozen Sections, Western blot / Immunoblot, Paraffin Sections.

Properties for Cytokeratin 13

Product Category	Antibodies
Quantity	0.5 ml
Synonyms	CK-13, CK13, K13, KRT-13, KRT13, Keratin type I cytoskeletal 13, Keratin-13, Review 009
Presentation	Supernatant
Reactivity	Fe, Hu, Rt
Applications	C, P, WB
Clonality	Monoclonal
Clone	DE-K13
Host	Mouse
Isotype	IgG2a
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	Acris Antibodies GmbH

Datasheet Extract

Immunogen	Swiss Prot Num: P13646 Immunogen: Detergent insoluble extract of human epidermis Genename: 3860
Property	+ KRT10
Antibody type	Ab
Application	Western Blot. Immunohistochemistry on aceton-fixed frozen and formalin-fixed paraffin embedded tissus: use a dilution of 1:25-1:50 in an ABC method (of 30 minutes at room temperature). Enzymatic predigestion of paraffin embedded tissues is not recommended prior to the immunostaining, as it may reduce the staining. Recommended positive control: Skin or tonsil
Background	Cytokeratin 13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus.
General Readings	Ivanyi et al. J Pathol 159: 7, 1989. Ivanyi et al. Differentiation 42: 124, 1989. Ivanyi et al. Cancer Res 50: 5143, 1990. Van Muijen et al. Exp Cell Res 171: 331, 1987.
Storage	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Format	State: Liquid tissue culture supernatant containing sodium azide as preservative Supernatant
Specificity	Specificity: This antibody recognizes keratin polypeptides of 53 (keratin 13) and 56.5 kD (keratin 10). It stains suprabasal cells in the epidermis, thymic Hassal's bodies, urothelium and non-cornifying stratified epithelia of vagina, ectocervix, tongue and esophagus. The antibody does not stain intraepithelial neoplasm and invasive squamous cell carcinoma. Cellular Localization: Cytoplasmic Species: Cat, Human, Rat.
Gene ID	3860
FocusOn and Reviews	Reviews: Antibodies to Cytokeratin Proteins - Product Review 09
Targets	Cytokeratin 13 antibody

Accessory Products

Proteins and/or Positive Controls

Positive controls for Cytokeratin 13 (1 products)

Catalog No.	Species
NBL1-12380	Cytokeratin 13 Lysate
		0.1 mg / €370.00
		Novus Biologicals Inc.

Recommended Secondary Antibodies for Cytokeratin 13 (8 products)

Catalog No.	Host	Pres.
R1253AP	Mouse IgG (H+L chain) antibody
	Rabbit	AP
			Acris Antibodies GmbH
R1253B	Mouse IgG (H+L chain) antibody
	Rabbit	Biotin
			Acris Antibodies GmbH
R1253F	Mouse IgG (H+L chain) antibody
	Rabbit	FITC
			Acris Antibodies GmbH
R1253HRP	Mouse IgG (H+L chain) antibody
	Rabbit	HRP
			Acris Antibodies GmbH
R1253TR	Mouse IgG (H+L chain) antibody
	Rabbit	Texas Red
			Acris Antibodies GmbH
R1403R	Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
	Rabbit	PE
			Acris Antibodies GmbH
R1405R	Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
	Goat	PE
			Acris Antibodies GmbH
R1455R	Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
	Donkey	PE
			Acris Antibodies GmbH