Cytokeratin 13 (+ KRT10) - NB120-9383

Product Description for Cytokeratin 13

Mouse anti Feline, Human Cytokeratin 13 DE-K13.
Properties: (+ KRT10)
Product is tested for Frozen Sections, Paraffin Sections, Western blot / Immunoblot.

Properties for Cytokeratin 13

Product Category	Antibodies
Quantity	0.1 ml
Synonyms	CK-13, CK13, K13, KRT-13, KRT13, Keratin type I cytoskeletal 13, Keratin-13, Review 009
Reactivity	Fe, Hu
Applications	C, P, WB
Clonality	Monoclonal
Clone	DE-K13
Host	Mouse
Shipping to	Not USA/Canada
PDF datasheet	View Datasheet
Manufacturer	Novus Biologicals Inc.

Datasheet Extract

Immunogen	Swiss Prot Num: P13646 Immunogen: Cytoskeletal preparation extracted from human ectocervical epithelium Genename: 3860
Property	+ KRT10
Antibody type	Ab
Application	flow cytometry / FACS analysis, Immunocytochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot, For formalin fixed paraffin embedded tissue, pretreatment with 0.1% pepsin in 0.1M HCL for 30 minutes at room temperature is required., flow cytometry / FACS analysis, Immunocytochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot,
Background	Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are designated 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium.Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
General Readings	General / background references:van Bommel PF et al. Expression of cytokeratin 10, 13, and involucrin as prognostic factors in low stage squamous cell carcinoma of the uterine cervix. Cancer 74:2314-20 (1994). Ivanyi D et al. Cytokeratins as markers of initial stages of squamous metaplasia in feline mammary carcinomas. Am J Vet Res 54:1095-102 (1993). Ivanyi D et al. Patterns of expression of feline cytokeratins in healthy epithelia and mammary carcinoma cells. Am J Vet Res 53:304-14 (1992).
Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format	Purification: protein A purified Buffer System: 15mM Sodium Azide Purity: protein A purified
Specificity	Specificity: This reacts with cytokeratin 10 and 13 in fixed cells and frozen tissue, but exclusively with cytokeratin 13 in formalin fixed paraffin embedded tissue. Species: Feline, Human
Gene ID	3860
FocusOn and Reviews	Reviews: Antibodies to Cytokeratin Proteins - Product Review 09
Targets	Cytokeratin 13 antibody

Accessory Products

Proteins and/or Positive Controls

Positive controls for Cytokeratin 13 (1 products)

Catalog No.	Species
NBL1-12380	Cytokeratin 13 Lysate
		0.1 mg / €370.00
		Novus Biologicals Inc.

Recommended Secondary Antibodies for Cytokeratin 13 (8 products)

Catalog No.	Host	Pres.
R1253AP	Mouse IgG (H+L chain) antibody
	Rabbit	AP
			Acris Antibodies GmbH
R1253B	Mouse IgG (H+L chain) antibody
	Rabbit	Biotin
			Acris Antibodies GmbH
R1253F	Mouse IgG (H+L chain) antibody
	Rabbit	FITC
			Acris Antibodies GmbH
R1253HRP	Mouse IgG (H+L chain) antibody
	Rabbit	HRP
			Acris Antibodies GmbH
R1253TR	Mouse IgG (H+L chain) antibody
	Rabbit	Texas Red
			Acris Antibodies GmbH
R1403R	Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
	Rabbit	PE
			Acris Antibodies GmbH
R1405R	Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
	Goat	PE
			Acris Antibodies GmbH
R1455R	Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
	Donkey	PE
			Acris Antibodies GmbH