AP06197PU-N Cytokeratin 16 antibody

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0.1 mg / €320.00
Delivery Time: 10 working days

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Rabbit anti Human, Mouse, Rat Cytokeratin 16

AP06197PU-N

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  • AP06197PU-N

Product Description for Cytokeratin 16

Rabbit anti Human, Mouse, Rat Cytokeratin 16.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot, Paraffin Sections.

Properties for Cytokeratin 16

Product Category Antibodies
Quantity 0.1 mg
Synonyms CK16, Cytokeratin-16, K16, KRT16, KRT16A, Keratin 16, Keratin type I cytoskeletal 16, Keratin-16, Review 009
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications E, P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH

Datasheet Extract

Immunogen
Swiss Prot Num:
P08779
Genename:
3868
Antibody type Ab
Application ELISA: 1/10000-1/20000.
Western Blots: 1/500-1/1000.
Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Background Keratin 16 is expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating.
Two cytokeratins, 6 and 16, are expressed when keratincytes are undergoing rapid turnover in various pathological states, wound healing, psoriasis and some carcinomas
Concentration 1.0 mg/ml
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: One year from despatch.
Format
Purification:
Affinity Chromatography using epitope-specific immunogen
Buffer System:
PBS, pH~7.2
Preservatives:
0.05% Sodium Azide
State:
Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, Mouse, Rat
Specificity
Specificity:
This antibody detects endogenous levels of Cytokeratin 16 protein.
Gene ID 3868
FocusOn and Reviews
Reviews:
Targets

Accessory Products

Proteins and/or Positive Controls

Proteins for Cytokeratin 16 (4 products)

Catalog No. Species Pres. Purity   Source  
H00003868-P01-10

Cytokeratin 16

Cytokeratin 16 Human Purified
10 µg / €350.00
  Abnova Taiwan Corp.
H00003868-P01-25

Cytokeratin 16

Cytokeratin 16 Human Purified
25 µg / €500.00
  Abnova Taiwan Corp.
H00003868-Q01-10

Cytokeratin 16

Cytokeratin 16 Human in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00003868-Q01-25

Cytokeratin 16

Cytokeratin 16 Human in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.

Positive controls for Cytokeratin 16 (2 products)

Catalog No. Species Pres. Purity   Source  
H00003868-T01

Cytokeratin-16 (KRT16) Lysate(Denatured)

Cytokeratin-16 (KRT16) Lysate(Denatured)
0.1 ml / €240.00
  Abnova Taiwan Corp.
NBL1-12383

Cytokeratin 16 Lysate

Western Blot: Cytokeratin 16 Lysate [NBL1-12383] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for KRT16
0.1 mg / €370.00
  Novus Biologicals Inc.