NBP1-42572 Cytokeratin 18 antibody

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0.1 mg / €340.00
Please visit the appropriate website of Acris Antibodies or contact your local Distributor to buy this product.

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Mouse anti Human, Rat Cytokeratin 18 CK-18

NBP1-42572

Product Description for Cytokeratin 18

Mouse anti Human, Rat Cytokeratin 18 CK-18.
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Paraffin Sections, Immunoprecipitation, Western blot / Immunoblot.

Properties for Cytokeratin 18

Product Category Antibodies
Target Category
Quantity 0.1 mg
Synonyms CK18, CYK18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, K18, KRT18, Keratin 18, Keratin type I cytoskeletal 18, Keratin-18
Reactivity Hu, Rt
Applications C, ICC/IF, IP, P, WB
Clonality Monoclonal
Clone CK-18
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P05783
Immunogen:
The human epidermal carcinoma A-431 and MCF-7 human breast cancer cell lines.,
Genename:
3875
Antibody type Ab
Add. information ,
Application This antibody is useful in Western Blot, Immunohistochemistry, Immunoprecipitation, Immunofluorescence., Western Blot 0.5-1ul/ml, Immunohistochemistry-Paraffin 1-2ul/ml, Immunohistochemistry-Frozen 0.5-2ul/ml.
Background Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie., skin) and non keratinizing cells (ie. mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. At least 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8.5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification. Cytokeratin 18 is an acidic keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas. Cytokeratin 18 exists in combination with Cytokeratin 8, a basic keratin. Hepatocellular carcinomas have been reportedly defined by the use of antibodies that recognize only Cytokeratins 8 and 18. This antibody reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
Affinity purified
Buffer System:
PBS
Specificity
Species:
Human, Rat
Gene ID 3875
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Accessory Products

Proteins and/or Positive Controls

Proteins for Cytokeratin 18 (8 products)

Catalog No. Species Pres. Purity   Source  
AR09362PU-N

Cytokeratin 18

Cytokeratin 18 Human Purified > 95 % (determined by SDS gelelectrophoresis)
0.25 mg / €530.00
  Acris Antibodies GmbH
AR09362PU-S

Cytokeratin 18

Cytokeratin 18 Human Purified > 95 % (determined by SDS gelelectrophoresis)
0.1 mg / €320.00
  Acris Antibodies GmbH
H00003875-P01-10

Cytokeratin 18

Cytokeratin 18 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00003875-P01-25

Cytokeratin 18

Cytokeratin 18 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.
H00003875-P02

Cytokeratin 18

Cytokeratin 18 Human Purified
10 µg / €420.00
  Abnova Taiwan Corp.
H00003875-P02-10

Cytokeratin 18

Cytokeratin 18 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00003875-P02-25

Cytokeratin 18

Cytokeratin 18 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.
BRP1006

Cytokeratin 18 (Active)

Cytokeratin 18 Human
0.1 mg / €320.00
  Biospes Co., Ltd

Positive controls for Cytokeratin 18 (3 products)

Catalog No. Species Pres. Purity   Source  
NBL1-12385

Cytokeratin 18 Lysate

Western Blot: Cytokeratin 18 Lysate [NBL1-12385] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for KRT18
0.1 mg / €370.00
  Novus Biologicals Inc.
NBL1-12386

Cytokeratin 18 Lysate

Western Blot: Cytokeratin 18 Lysate [NBL1-12386] - Western Blot experiments. Left-Control; Right -Over-expression Lysate for KRT18.
0.1 mg / €370.00
  Novus Biologicals Inc.
H00003875-T01

KRT18 293T Cell Transient Overexpression Lysate(Denatured)

KRT18 293T Cell Transient Overexpression Lysate(Denatured)
0.1 ml / €240.00
  Abnova Taiwan Corp.
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