BM6004P Cytokeratin 8 antibody

Swiss Prot Num:

P05787

Immunogen:

Cytoskeleton preparation containing Cytokeratin 8.

Genename:

3856

• Guelstein VI, Tchypysheva TA, Ermilova VD, Litvinova LV, Troyanovsky SM, Bannikov GA. Monoclonal antibody mapping of keratins 8 and 17 and of vimentin in normal human mammary gland, benign tumors, dysplasias and breast cancer. Int J Cancer. 1988 Aug 15;42(2):147-53. PubMed PMID: 2456993.
• Troyanovsky SM, Guelstein VI, Tchipysheva TA, Krutovskikh VA, Bannikov GA. Patterns of expression of keratin 17 in human epithelia: dependency on cell position. J Cell Sci. 1989 Jul;93 ( Pt 3):419-26. PubMed PMID: 2481679.
• Ljubimov AV, Bartek J, Couchman JR, Kapuller LL, Veselov VV, Kovarik J, et al. Distribution of individual components of basement membrane in human colon polyps and adenocarcinomas as revealed by monoclonal antibodies. Int J Cancer. 1992 Feb 20;50(4):562-6. PubMed PMID: 1371500.
• Litvinov SV, van Driel W, van Rhijn CM, Bakker HA, van Krieken H, Fleuren GJ, et al. Expression of Ep-CAM in cervical squamous epithelia correlates with an increased proliferation and the disappearance of markers for terminal differentiation. Am J Pathol. 1996 Mar;148(3):865-75. PubMed PMID: 8774141.

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Buffer System:

PBS with 0.02% Sodium Azide as preservative and 0.1% BSA and 50% glycerol as stabilizer.

State:

Liquid purified IgG fraction
Purified

Species reactivity (tested):

Human, Zebrafish.

Specificity:

H1 reacts with glandular epithelial cells (endocrine and exocrine) as well as mesothelial cells of the digestive, respiratory and urogenital tract and most adenocarcinomas derived from these cells.