AP21856PU-N Endoplasmin / HSP90B1 / TRA1 antibody

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0.1 mg / €320.00
Delivery Time: 5-7 working days

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Rabbit anti Equine, Human, Monkey, Mouse Endoplasmin / HSP90B1 / TRA1

AP21856PU-N

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  • AP21856PU-N

Product Description for Endoplasmin / HSP90B1 / TRA1

Rabbit anti Equine, Human, Monkey, Mouse Endoplasmin / HSP90B1 / TRA1.
Presentation: Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for Endoplasmin / HSP90B1 / TRA1

Product Category Antibodies
Quantity 0.1 mg
Synonyms 94 kDa glucose-regulated protein, FocusOn097, GRP94, Heat shock protein 90 kDa beta member 1, Tumor rejection antigen 1
Presentation Purified
Reactivity Eq, Hu, Mky, Ms
Applications P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P14625
Immunogen:
A portion of amino acids 590-640 of human GRP94
Genename:
7184
Remarks:
100% homologous in human, chimpanzee, monkey and mouse
94% homologous in rat and cow
89% homologous in chicken
84% homologous in zebrafish
81% homologous in xenopus
Antibody type Ab
Application Immunohistochemistry on paraffin sections: 10 µg/ml.
Western blot: 0.5 - 2 µg/ml.
Recommended Positive Control: 3T3 and RAW cell lysate
Background GRP94 is a 803 amino acid protein belonging to the heat shock protein 90 family. It acts as a molecular chaperone that functions in the processing and transport of secreted proteins. GRP94 and its N-terminal fragment stimulates CTL expansion and maturation of human monocyte-derived dendritic cells (MDDC). It plays a central role in innate as well as acquired immunity, maturation and chemotaxis of dendritic cells, Ab production, cross-priming, as a potential marker in breast cancer and is a peptide acceptor in endoplasmic reticulum and an accessory to peptide loading of MHC class I molecules. Expression of GRP94 suppressed A23187-induced apoptosis and stabilized calcium homeostasis. GRP94 is expressed in melanoma or liver metastases of colon carcinoma cells, human gastric carcinoma BGC-823 cells.
Concentration 0,5 mg/ml
General Readings
  • Zhang, Y. et al. Biochem. Biophys. Res. Commun. 344:581-587 (2006).
  • Esseghir, S. et al. Clin. Cancer. Res. 13:3164-3173 (2007).
  • Cho, NH. et al. Microbio. Immunol. 48:297-305 (2004).
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein G chromatography
Buffer System:
PBS containing 0.2% gelatin and 0.05% sodium azide
State:
Liquid purified Ig fraction
Purified
Species Reactivity
Species reactivity (expected):
Rat, Cow, Zebrafish, Xenopus, Chicken.
Species reactivity (tested):
Chimpanzee, Horse, Human, New World monkey, Mouse.
Specificity
Specificity:
This antibody reacts to GRP94.
Gene ID 7184
Targets

Accessory Products

Proteins and/or Positive Controls

Proteins for Endoplasmin / HSP90B1 / TRA1 (7 products)

Catalog No. Species Pres. Purity   Source  
AR09147PU-L

Endoplasmin / HSP90B1 / TRA1 (22-803, His-tag)

Recombinant human HSP90B1 (GRP94), aa 22-803, His-tagged: 15% SDS-PAGE (3 µg) Human Purified > 90 % E. coli
0.5 mg / €1,500.00
  Acris Antibodies GmbH
AR09147PU-N

Endoplasmin / HSP90B1 / TRA1 (22-803, His-tag)

Recombinant human HSP90B1 (GRP94), aa 22-803, His-tagged: 15% SDS-PAGE (3 µg) Human Purified > 90 % E. coli
0.1 mg / €520.00
  Acris Antibodies GmbH
H00007184-P01-10

Endoplasmin / HSP90B1 / TRA1

Endoplasmin / HSP90B1 / TRA1 Human in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00007184-P01-25

Endoplasmin / HSP90B1 / TRA1

Endoplasmin / HSP90B1 / TRA1 Human in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.
H00007184-P02

Endoplasmin / HSP90B1 / TRA1

Endoplasmin / HSP90B1 / TRA1 Human Purified
10 µg / €420.00
  Abnova Taiwan Corp.
H00007184-P02-10

Endoplasmin / HSP90B1 / TRA1

Endoplasmin / HSP90B1 / TRA1 Human Purified
10 µg / €350.00
  Abnova Taiwan Corp.
H00007184-P02-25

Endoplasmin / HSP90B1 / TRA1

Endoplasmin / HSP90B1 / TRA1 Human Purified
25 µg / €500.00
  Abnova Taiwan Corp.

Positive controls for Endoplasmin / HSP90B1 / TRA1 (1 products)

Catalog No. Species Pres. Purity   Source  
NBL1-11746

GRP94 Lysate

Western Blot: GRP94 Lysate [NBL1-11746] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for HSP90B1
0.1 mg / €370.00
  Novus Biologicals Inc.