Product Description for Estrogen receptor beta
Rabbit anti Human Estrogen receptor beta.
Properties: (N-term)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.
Properties: (N-term)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.
Properties for Estrogen receptor beta
| Product Category | Antibodies |
|---|---|
| Quantity | 50 µg |
| Synonyms | ER-beta, ESR2, ESTRB, FocusOn050, FocusOn098, NR3A2, Nuclear receptor subfamily 3 group A member 2 |
| Presentation | Aff - Purified |
| Reactivity | Hu |
| Applications | P, WB |
| Clonality | Polyclonal |
| Host | Rabbit |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | Acris Antibodies GmbH |
Datasheet Extract
| Immunogen |
|
|---|---|
| Property | N-term |
| Antibody type | Ab |
| Application | Western blot. Immunohistochemistry on Paraffin Sections: 10 µg/ml. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. |
| Background | Estrogen receptor beta (ER beta), a NR3 Steroid Receptor, has been shown to have physiological functions in the central nervous system, cardiovascular system, immune system, urogenital tract, gastrointestinal tract, and in bone, kidney, and lung. Mice lacking the gene for ER beta show defective ovary development, reduced fertility, abnormal bladder and prostate development, and impaired vascular system functions that lead to hypertension in aging. ER beta is phosphorylated upon ligand activation and binds to target DNA as a homodimer. At least eight alternatively spliced isoforms of ER beta have been documented, many of which show tissue-specific expression patterns. A novel and functionally distinct isoform of human ER beta (ER beta548), which includes an extended amino-terminal domain has been identified recently by Wilkinson et al. 2002. ER beta has been suggested to affect carcinogenesis in smooth muscle, urogenital tract, breast, and colonic tissues. |
| Concentration | 0.2 mg/ml |
| Storage | Store the antibody undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch. |
| Format |
|
| Species Reactivity |
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| Specificity |
|
| Gene ID | 2100 |
| FocusOn and Reviews | |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for Estrogen receptor beta (2 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00002100-Q01-10 |
Estrogen receptor beta |
||||||
 |
Human | in vitro transl. |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00002100-Q01-25 |
Estrogen receptor beta |
||||||
|
Human | in vitro transl. |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
Positive controls for Estrogen receptor beta (1 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| NBL1-10345 |
Estrogen Receptor beta Lysate |
||||||
![Western Blot: Estrogen Receptor beta Lysate [NBL1-10345] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for ESR2](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/Estrogen Receptor beta Lysate-Western Blot-NBL1-10345-img0001.jpg) |
0.1 mg /
€500.00
|
||||||
| Novus Biologicals Inc. | |||||||
Recommended Secondary Antibodies for Estrogen receptor beta (6 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | TRITC | |||||
| Acris Antibodies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
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