Product Description for Estrogen-related receptor gamma
Rabbit anti Human, Mouse, Rat Estrogen-related receptor gamma.
Presentation: Aff - Purified
Product is tested for Paraffin Sections.
Presentation: Aff - Purified
Product is tested for Paraffin Sections.
Properties for Estrogen-related receptor gamma
| Product Category | Antibodies |
|---|---|
| Quantity | 50 µg |
| Synonyms | ERR gamma-2, ERR3, ERRG2, ESRRG, Estrogen receptor-related protein 3, FocusOn050, KIAA0832, NR3B3, Nuclear receptor subfamily 3 group B member 3 |
| Presentation | Aff - Purified |
| Reactivity | Hu, Ms, Rt |
| Applications | P |
| Clonality | Polyclonal |
| Host | Rabbit |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | Acris Antibodies GmbH |
Datasheet Extract
| Immunogen |
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|---|---|
| Antibody type | Ab |
| Application | Immunohistochemistry with Formalin Fixed Paraffin Embedded Tissues: 34 µg/ml Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. |
| Background | Estrogen receptor-related receptor (ERR gamma), a NR3 Steroid Receptor, has been suggested to affect differentiation of the brain, heart, and kidney. ERR gamma binds as a monomer to an extended half-site of the ERRE type (TCAAGGTCA). ERR gamma has been shown to interact with PGC-1 alpha and has been implicated in the regulation of mitochondrial energy metabolism. In humans, ERR gamma pre-mRNA undergoes extensive alternative splicing at the 5 end, yielding at least six mRNA splice variants and two protein isoforms that differ by 23 amino acids in the N terminus. ERR gamma has been shown to be overexpressed in breast tumors, and its expression is correlated with levels of ErbB4, a likely indicator of preferred clinical course. As a result, ERR gamma has been suggested to be a potential biomarker for favorable clinical course and, possibly, hormonal sensitivity, and as a candidate target for therapeutic development. ERR gamma expression at the mRNA and protein levels is isoform- and tissue-specific in humans. ERR gamma expression has been documented in human heart, brain, placenta, skeletal muscle, kidney, pancreas, spleen, prostate, testis, and small intestine. ESTs have been isolated from human tissue libraries, including cancerous fetus, uterus, lung, breast, head/neck, colon, skin, eye, adrenal, normal placenta, kidney, brain, pineal, ear, and heart. |
| Concentration | 1.0 mg/ml |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Format |
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| Species Reactivity |
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| Specificity |
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| Gene ID | 2104 |
| FocusOn and Reviews | |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for Estrogen-related receptor gamma (3 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00002104-P02 |
Estrogen-related receptor gamma |
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 |
Human | Purified |
10 µg /
€420.00
|
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| Abnova Taiwan Corp. | |||||||
| H00002104-P02-10 |
Estrogen-related receptor gamma |
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|
Human | Purified |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00002104-P02-25 |
Estrogen-related receptor gamma |
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|
Human | Purified |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
Positive controls for Estrogen-related receptor gamma (2 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00002104-T01 |
ESRRG 293T Cell Transient Overexpression Lysate(Denatured) |
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|
0.1 ml /
€240.00
|
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| Abnova Taiwan Corp. | |||||||
| NBL1-10347 |
Estrogen Related Receptor gamma Lysate |
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![Western Blot: Estrogen Related Receptor gamma Lysate [NBL1-10347] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for ESRRG](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/Estrogen Related Receptor gamma Lysate-Western Blot-NBL1-10347-img0001.jpg) |
0.1 mg /
€500.00
|
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| Novus Biologicals Inc. | |||||||
Recommended Secondary Antibodies for Estrogen-related receptor gamma (6 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | TRITC | |||||
| Acris Antibodies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
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