AP05919PU-N GABRB3 (C-term) antibody

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0.1 ml / €470.00
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Rabbit anti Mouse, Rat GABRB3

AP05919PU-N

Product Description for GABRB3

Rabbit anti Mouse, Rat GABRB3.
Properties: (C-term)
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for GABRB3

Product Category Antibodies
Quantity 0.1 ml
Synonyms GABA A receptor subunit beta-3, GABRB-3, Gamma-aminobutyric acid receptor subunit beta-3, Review 022
Presentation Purified
Reactivity Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH

Datasheet Extract

Immunogen
Swiss Prot Num:
P63079
Immunogen:
Fusion protein within the cytosolic loop of rat GABA A receptor beta 3 subunit.
Genename:
24922
Property C-term
Antibody type Ab
Application Western Blot: 1:1000; detects a band of approximately 53 kDa in cerebellum lysates.
Background GABA A receptors are GABA gated chloride channels, which are important mediators of neuronal inhibition in the mammalian central nervous system. Activation of the GABA A site results in increased intracellular chloride concentration and hyperpolarization of the cell.
GABA A receptors are pentameric structures assembled from a family of distinct subunits. At least fourteen distinct subunits have been identified, which show distinct patterns of temporal and spatial expression.
GABA A receptors may be modulated by several drug types including benzodiazepines and barbiturates, and by phosphorylation by protein kinase C (PKC) and protein kinase A (PKA).
Caution (A full Health and Safety assessment is available upon request) This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
General Readings
  • Burt, D.R. et al. (1991) GABAA receptor subtypes: from pharmacology to molecular biology. FASEB. J. 5: 2916 - 2923.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography
Buffer System:
10mM HEPES pH7.5 containing 0.09% Sodium Azide, 0.01% Bovine Serum Albumin and 50% Glycerol
State:
Liquid purified Ig
Purified
Specificity
Specificity:
This antibody is specific for the beta 3 subunit of gamma-aminobutyric acid A (GABA A) receptor.
Species:
Rat, Mouse.
Gene ID 24922
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