Heat shock protein 65 / HSP65

Product Description for Heat shock protein 65 / HSP65

Mouse anti Mycobacteria Heat shock protein 65 / HSP65 BDI578.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for Heat shock protein 65 / HSP65

Product Category	Antibodies
Quantity	0.1 mg
Synonyms	60 kDa chaperonin 2, Antigen A, Cell wall protein A, MT0456, MTV037.04, Protein Cpn60-2, Rv0440, groEL protein 2, groEL-2, groEL2, groL2, hsp65
Presentation	Purified
Reactivity	Mycobacteria
Applications	E, WB
Clonality	Monoclonal
Clone	BDI578
Host	Mouse
Isotype	IgG2a
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	Acris Antibodies GmbH

Datasheet Extract

Immunogen	Swiss Prot Num: P0A520 Immunogen: Purified protein derivative (PPD) Genename: 886354
Antibody type	Ab
Application	ELISA. Western Blot.
Background	Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure; most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65. The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method.
Concentration	0,1 mg/ml (OD280nm, E0.1% = 1.4)
Storage	Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Format	Purification: >90% pure. Protein A chromatography Buffer System: 0.01M PBS, pH 7.2 containing 0,09% sodium azide State: Liquid purified Ig Purified
Specificity	Specificity: This antibody is reactive with Hsp65 (GroEL) of M. tuberculosis. Does not react with M. bovis, M. avium, M. phlei, M. parafortuitum, Rhodococcus sp., B. subtilis, S. pneumoniae, and E. coli.
Gene ID	886354
FocusOn and Reviews	Reviews: Antibodies to Heat Shock Proteins - Product Review 03
Targets	Heat shock protein 65 / HSP65 antibody

Accessory Products

Proteins and/or Positive Controls

Proteins for Heat shock protein 65 / HSP65 (4 products)

Catalog No.	Species	Pres.	Purity	Source
AR03023PU-L	Heat shock protein 65 / HSP65 (native)
	Mycobacteria	Aff - Purified	> 90 %	E. coli	0.2 mg / €760.00
					Acris Antibodies GmbH
AR03023PU-N	Heat shock protein 65 / HSP65 (native)
	Mycobacteria	Aff - Purified	> 90 %	E. coli	0.1 mg / €460.00
					Acris Antibodies GmbH
AR03023PU-S	Heat shock protein 65 / HSP65 (native)
	Mycobacteria	Aff - Purified	> 90 %	E. coli	50 µg / €360.00
					Acris Antibodies GmbH
8HSP65	Heat shock protein 65 / HSP65
		Purified	> 95 %	E. coli	0.1 mg / €640.00
					HyTest Ltd.

Recommended Secondary Antibodies for Heat shock protein 65 / HSP65 (8 products)

Catalog No.	Host	Pres.
R1253AP	Mouse IgG (H+L chain) antibody
	Rabbit	AP
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R1253B	Mouse IgG (H+L chain) antibody
	Rabbit	Biotin
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R1253F	Mouse IgG (H+L chain) antibody
	Rabbit	FITC
			Acris Antibodies GmbH
R1253HRP	Mouse IgG (H+L chain) antibody
	Rabbit	HRP
			Acris Antibodies GmbH
R1253TR	Mouse IgG (H+L chain) antibody
	Rabbit	Texas Red
			Acris Antibodies GmbH
R1403R	Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
	Rabbit	PE
			Acris Antibodies GmbH
R1405R	Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
	Goat	PE
			Acris Antibodies GmbH
R1455R	Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
	Donkey	PE
			Acris Antibodies GmbH