Heat Shock Protein 90 / HSP90 (alpha + beta) - NB120-1429

Product Description for Heat Shock Protein 90 / HSP90

Mouse anti Bovine, Human, Monkey, Mouse, Rabbit, Rat Heat Shock Protein 90 / HSP90 S88.
Properties: (alpha + beta)
Presentation: Serum
Product is tested for Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Paraffin Sections, Western blot / Immunoblot.

Properties for Heat Shock Protein 90 / HSP90

Product Category	Antibodies
Quantity	50 µg
Synonyms	HSP-84, HSP-86, HSP-90, HSP84, HSP86, HSP90A, HSP90AA1, HSP90AB1, HSP90B, HSPC1, HSPC2, HSPCA, HSPCB, Heat shock protein HSP 90-alpha, Heat shock protein HSP 90-beta, Renal carcinoma antigen NY-REN-38, Review 003
Presentation	Serum
Reactivity	Bov, Hu, Mky, Ms, Rb, Rt
Applications	ICC/IF, IP, P, WB
Clonality	Monoclonal
Clone	S88
Host	Mouse
Isotype	IgG1
Shipping to	Not USA/Canada
PDF datasheet	View Datasheet
Manufacturer	Novus Biologicals Inc.

Datasheet Extract

Immunogen	Swiss Prot Num: P08238 Immunogen: Full length native protein (purified) (Achlya ambisexualis). Genename: 3326
Property	alpha + beta
Antibody type	Ab
Application	Immunohistochemistry-Frozen, immunoprecipitation, Western Blot, This antibody is useful for Immunoprecipitation,Western Blot and Immunohistochemistry-Frozen., immunoprecipitation 4 ug/ml, Western Blot 1 ug/ml, Immunohistochemistry-Frozen 10 - 20 ug/ml
Background	In mammalian cells there are at least two Hsp90 isoforms, Hsp90a and Hsp90b which are encoded by separate genes. These ubiquitous and highly conserved proteins account for 1-2% of all cellular proteins in most cells. Hsp90 is part of the cells powerful network of chaperones to fight the deleterious consequences of protein unfolding caused by nonphysiological conditions. However, in the absence of stress, Hsp90 is a necessary component of fundamental cellular processes such as hormone signaling and cell cycle control. In this context several key regulatory proteins such as steriod receptors, cell cycle kinases involved in signal transduction and p53 have been identified as substrates of Hsp90. It has been suggested that Hsp90 acts as a capacitor for morphological evolution by buffering widespread variation, which may affect morphogenic pathways.
Concentration	0.2 mg/ml
General Readings	This product has been used in:Riehl RM et al. Immunological evidence that the nonhormone binding component of avian steroid receptors exists in a wide range of tissues and species. Biochemistry 24:6586-91 (1985). Sanchez ER et al. Evidence that the 90-kDa phosphoprotein associated with the untransformed L-cell glucocorticoid receptor is a murine heat shock protein. J Biol Chem 260:12398-401 (1985).
Storage	Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Format	Purification: Whole antisera Buffer System: Thimerosal Purity: Whole antisera State: Serum
Specificity	Specificity: The recognizes a 90 kDa protein, corresponding to the apparent molecular weight of Hsp90 on SDS-PAGE immunoblots. This detects both Hsp90 alpha and beta. Species: Bovine, Canine, Chicken, Guinea Pig, Human, Mouse, Porcine, Primate, Rabbit, Rat, Sheep
Gene ID	3326
FocusOn and Reviews	Reviews: Antibodies to Heat Shock Proteins - Product Review 03
Targets	HSP90AB1 / HSP90 beta antibody

Accessory Products

Proteins and/or Positive Controls

Proteins for Heat Shock Protein 90 / HSP90 (2 products)

Catalog No.	Species	Pres.
H00003326-P01-10	HSP90AB1 / HSP90 beta
	Human	Purified	10 µg / €350.00
			Abnova Taiwan Corp.
H00003326-P01-25	HSP90AB1 / HSP90 beta
	Human	Purified	25 µg / €500.00
			Abnova Taiwan Corp.

Positive controls for Heat Shock Protein 90 / HSP90 (1 products)

Catalog No.	Species
NBL1-11745	Hsp90B Lysate
		0.1 mg / €370.00
		Novus Biologicals Inc.

Recommended Secondary Antibodies for Heat Shock Protein 90 / HSP90 (8 products)

Catalog No.	Host	Pres.
R1253AP	Mouse IgG (H+L chain) antibody
	Rabbit	AP
			Acris Antibodies GmbH
R1253B	Mouse IgG (H+L chain) antibody
	Rabbit	Biotin
			Acris Antibodies GmbH
R1253F	Mouse IgG (H+L chain) antibody
	Rabbit	FITC
			Acris Antibodies GmbH
R1253HRP	Mouse IgG (H+L chain) antibody
	Rabbit	HRP
			Acris Antibodies GmbH
R1253TR	Mouse IgG (H+L chain) antibody
	Rabbit	Texas Red
			Acris Antibodies GmbH
R1403R	Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
	Rabbit	PE
			Acris Antibodies GmbH
R1405R	Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
	Goat	PE
			Acris Antibodies GmbH
R1455R	Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
	Donkey	PE
			Acris Antibodies GmbH