AP16315PU-N HIP14 / ZDHHC17 (C-term) antibody

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0.1 mg / €270.00
Delivery Time: 3-5 working days

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Goat anti Canine, Chimpanzee, Human, Mouse, Rat HIP14 / ZDHHC17

Product Description for HIP14 / ZDHHC17

Goat anti Canine, Chimpanzee, Human, Mouse, Rat HIP14 / ZDHHC17.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for HIP14 / ZDHHC17

Product Category Antibodies
Quantity 0.1 mg
Synonyms DHHC-17, FocusOn132, HIP3, HSPC294, HYPH, Huntingtin-interacting protein 14, Huntingtin-interacting protein 3, Huntingtin-interacting protein H, KIAA0946, Palmitoyltransferase ZDHHC17, Zinc finger DHHC domain-containing protein 17
Presentation Aff - Purified
Reactivity Can, Chimp, Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Goat
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH

Datasheet Extract

Immunogen
Swiss Prot Num:
Q8IUH5
Immunogen:
Peptide with sequence CYDQISGSGYQLV, from the C Terminus of the protein sequence according to NP_056151.2.
Genename:
23390
Property C-term
Antibody type Ab
Application Peptide ELISA: Detection Limit Dilution: 1/8000.
Western blot: 1-3 µg/ml. Approx 70kDa band observed in Human and Mouse Brain lysates (Calculated MW of 72.7kDa according to NP_056151.1).
Background ZDHHC17 (HIP14) is a neuronal palmitoyl transferase. Palmitoylation is critical for trafficking and function of signaling molecules, neurotransmitter receptors, and synaptic scaffolding proteins in neurons.
ZDHHC17 causes cellular transformation. It has been shown that mRNA encoding ZDHHC17 is up-regulated in a number of types of human tumors, thus ZDHHC17 and other PATs (palmitoyl acyltransferases) are potential targets for new anticancer drugs.
Concentration 0.5 mg/ml
General Readings
  • Huang K, Yanai A, Kang R, Arstikaitis P, Singaraja RR, Metzler M, et al. Huntingtin-interacting protein HIP14 is a palmitoyl transferase involved in palmitoylation and trafficking of multiple neuronal proteins. Neuron. 2004 Dec 16;44(6):977-86. PubMed PMID: 15603740.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Buffer System:
Tris saline, pH 7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer
State:
Liquid purified IgG fraction
Aff - Purified
Species Reactivity
Species reactivity (expected):
Rat, Canine (Dog) and Bovine.
Species reactivity (tested):
Human, Mouse.
Specificity
Specificity:
This antibody recognizes HIP14/ZDHHC17.
Gene ID 23390
FocusOn and Reviews
FocusOns:
Targets

Accessory Products

Proteins and/or Positive Controls

Proteins for HIP14 / ZDHHC17 (1 products)

Catalog No. Species Pres. Purity   Source  
H00023390-P01-02

HIP14 / ZDHHC17

HIP14 / ZDHHC17 Human in vitro transl.
2 µg / €250.00
  Abnova Taiwan Corp.

Positive controls for HIP14 / ZDHHC17 (1 products)

Catalog No. Species Pres. Purity   Source  
NBL1-18003

ZDHHC17 Lysate

Western Blot: ZDHHC17 Lysate [NBL1-18003] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for ZDHHC17
0.1 mg / €370.00
  Novus Biologicals Inc.