NB110-61640 HSP90AB1 / HSP90 beta antibody

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0.2 mg / €390.00
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Mouse anti Chicken, Human, Rabbit HSP90AB1 / HSP90 beta H90-10

NB110-61640

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Product Description for HSP90AB1 / HSP90 beta

Mouse anti Chicken, Human, Rabbit HSP90AB1 / HSP90 beta H90-10.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Paraffin Sections, Immunoprecipitation, Western blot / Immunoblot.

Properties for HSP90AB1 / HSP90 beta

Product Category Antibodies
Quantity 0.2 mg
Synonyms HSP84, HSP90B, HSPC2, HSPCB, Heat shock 84 kDa, Heat shock protein HSP 90-beta, Review 003
Presentation Purified
Reactivity Chk, Hu, Rb
Applications E, ICC/IF, IP, P, WB
Clonality Monoclonal
Clone H90-10
Host Mouse
Isotype IgG2a
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P08238
Immunogen:
Recombinant human hsp90beta.
Genename:
3326
Antibody type Ab
Add. information Research Areas: Cellular Markers
Application ELISA, immunoprecipitation, Western Blot, ELISA, Immunoprecipitation and Western Blot , ELISA , immunoprecipitation , Western Blot
Background HSP90 is an abundantly and ubiquitously expressed heat shock protein. It is understood to exist in two principal forms alpha and beta, which share 85% sequence amino acid homology. The two isoforms of Hsp90, are expressed in the cytosolic compartment (1). Despite the similarities, HSP90alpha exists predominantly as a homodimer while HSP90beta; exists mainly as a monomer.(2) From a functional perspective, hsp90 participates in the folding, assembly, maturation, and stabilization of specific proteins as an integral component of a chaperone complex. (3-6) Furthermore, Hsp90 is highly conserved between species; having 60% and 78% amino acid similarity between mammalian and the corresponding yeast and Drosophila proteins, respectively. Hsp90 is a highly conserved and essential stress protein that is expressed in all eukaryotic cells. Despite it's label of being a heat-shock protein, hsp90 is one of the most highly expressed proteins in unstressed cells (1
Concentration 1 mg/ml
General Readings
  • Nemoto, T. et al. (1997) J.Biol Chem. 272, 26179-26187.
  • Minami, Y, et al. (1991), J.Biol Chem. 266, 10099-10103.
  • Arlander SJH, et al. (2003) J Biol Chem 278, 52572-52577.
  • Pearl H, et al. (2001) Adv Protein Chem 59,157-186.
  • Neckers L, et al. (2002) Trends Mol Med 8:S55-S61.
  • Pratt W, Toft D. (2003) Exp Biol Med 228:111-133.
  • Pratt W, Toft D. (1997) Endocr Rev 18,306–360.
  • Pratt WB. (1998) Proc Soc Exptl Biol Med 217, 420–434.
  • Whitesell L, et al. (1994) Proc Natl Acad Sci USA 91, 8324–8328.
  • Barent, R. L. (1998) Mol. Endocrinol. 12, 342-354
  • Loo. M.A. (1998) EMBO J. 17, 6879-6887.
Storage Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Format
Purification:
protein G purified
Buffer System:
0.09% Sodium Azide
Purity:
protein G purified
State:
Purified
Specificity
Specificity:
Detects 90kD proteins corresponding to the molecular mass of hsp90beta.
Species:
Chicken, Human, Rabbit, Rat
Gene ID 3326
FocusOn and Reviews
Reviews:
Targets

Accessory Products

Proteins and/or Positive Controls

Proteins for HSP90AB1 / HSP90 beta (2 products)

Catalog No. Species Pres. Purity   Source  
H00003326-P01-10

HSP90AB1 / HSP90 beta

HSP90AB1 / HSP90 beta Human Purified
10 µg / €350.00
  Abnova Taiwan Corp.
H00003326-P01-25

HSP90AB1 / HSP90 beta

HSP90AB1 / HSP90 beta Human Purified
25 µg / €500.00
  Abnova Taiwan Corp.

Positive controls for HSP90AB1 / HSP90 beta (1 products)

Catalog No. Species Pres. Purity   Source  
NBL1-11745

Hsp90B Lysate

Western Blot: Hsp90B Lysate [NBL1-11745] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for HSP90AB1
0.1 mg / €370.00
  Novus Biologicals Inc.