Product Description for HSPA5 / GRP78
Rabbit anti Human, Mouse, Rat HSPA5 / GRP78.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot, Paraffin Sections.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot, Paraffin Sections.
Properties for HSPA5 / GRP78
| Product Category | Antibodies |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | 78 kDa glucose-regulated protein, BiP, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, FocusOn097, Heat shock 70 kDa protein 5, Immunoglobulin heavy chain-binding protein |
| Presentation | Aff - Purified |
| Reactivity | Hu, Ms, Rt |
| Applications | E, ICC/IF, P, WB |
| Clonality | Polyclonal |
| Host | Rabbit |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | Acris Antibodies GmbH |
Datasheet Extract
| Immunogen |
|
|---|---|
| Antibody type | Ab |
| Application | ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200. Immunohistochemistry on Paraffin Sections: 1/50-1/200. |
| Background | The HSP 70 family comprises four highly conserved proteins, HSP 70, HSC 70, GRP 75 and GRP 78, which serve a variety of roles. They act as molecular chaperones facilitating the assembly of multi-protein complexes, participate in the translocation of polypeptides across cell membranes and to the nucleus, and aid in the proper folding of nascent polypeptide chains. HSC 70, GRP 75 and GRP 78 are constitutively expressed in primate cells. HSP 70 expression is strongly induced in response to heat stress. HSP 70 and HSC 70, which are found in both the cytosol and nucleus of mammalian cells, play key roles in the cytosolic endoplasmic reticulum and mitochondrial import machinery. They are involved in chaperoning nascent polypeptide chains and in protecting cells against the accumulation of improperly folded proteins. GRP 78 is localized in the endoplasmic reticulum, where it receives imported secretory proteins and is involved in the folding and translocation of nascent peptide chains. Research indicates that members of the HSP 70 family may act as force-generating motors, relying on the hydrolysis of ATP for their activity. |
| Concentration | 1.0 mg/ml |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: One year from despatch. |
| Format |
|
| Specificity |
|
| Gene ID | 3309 |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for HSPA5 / GRP78 (12 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| AR03021PU-L |
HSPA5 / GRP78 (Active Protein) |
||||||
 |
Human | Purified | > 90 % | E. coli |
0.2 mg /
€560.00
|
||
| Acris Antibodies GmbH | |||||||
| AR03021PU-N |
HSPA5 / GRP78 (Active Protein) |
||||||
|
Human | Purified | > 90 % | E. coli |
0.1 mg /
€410.00
|
||
| Acris Antibodies GmbH | |||||||
| AR03021PU-S |
HSPA5 / GRP78 (Active Protein) |
||||||
|
Human | Purified | > 90 % | E. coli |
50 µg /
€280.00
|
||
| Acris Antibodies GmbH | |||||||
| AR09764PU-L |
HSPA5 / GRP78 (20-650, His-tag) |
||||||
 |
Human | Purified | > 90 % | High-5 Insect cells |
0.5 mg /
€750.00
|
||
| Acris Antibodies GmbH | |||||||
| AR09764PU-N |
HSPA5 / GRP78 (20-650, His-tag) |
||||||
|
Human | Purified | > 90 % | High-5 Insect cells |
0.1 mg /
€300.00
|
||
| Acris Antibodies GmbH | |||||||
| NBC1-18378 |
HSPA5 / GRP78 |
||||||
![SDS-Page: GRP78 Protein [NBC1-18378] - BIP, 71 kDa (640 aa) with a purity of 90% by SDS - PAGE](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/GRP78 Protein-SDS-Page-NBC1-18378-img0001.jpg) |
0.1 mg /
€390.00
|
||||||
| Novus Biologicals Inc. | |||||||
| NBP1-50908-0.1 |
HSPA5 / GRP78 |
||||||
|
Human | Purified |
0.1 mg /
€340.00
|
||||
| Novus Biologicals Inc. | |||||||
| NBP1-50908-0.5 |
HSPA5 / GRP78 |
||||||
|
Human | Purified |
0.5 mg /
€740.00
|
||||
| Novus Biologicals Inc. | |||||||
| H00003309-P01-10 |
HSPA5 / GRP78 |
||||||
|
Human | in vitro transl. |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00003309-P01-25 |
HSPA5 / GRP78 |
||||||
|
Human | in vitro transl. |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00003309-Q01-10 |
HSPA5 / GRP78 |
||||||
|
Human | Purified |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00003309-Q01-25 |
HSPA5 / GRP78 |
||||||
|
Human | Purified |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
Recommended Secondary Antibodies for HSPA5 / GRP78 (6 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | TRITC | |||||
| Acris Antibodies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
Compare Products
You have no items to compare.
My Cart
You have no items in your shopping cart.
Antibody Location Service
Over 230,000 products but you can't find the right antibody for your protein or application?
Acris will do the search for you!
