AP16633PU-N KLK5 / Kallikrein-5 antibody

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0.1 mg / €270.00
Please visit the appropriate website of Acris Antibodies or contact your local Distributor to buy this product.

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Goat anti Canine, Human, Rat KLK5 / Kallikrein-5

Product Description for KLK5 / Kallikrein-5

Goat anti Canine, Human, Rat KLK5 / Kallikrein-5.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for KLK5 / Kallikrein-5

Product Category Antibodies
Quantity 0.1 mg
Synonyms FocusOn006, KLK-5, KLK-L2, Kallikrein-Like Protein 2, SCTE, Stratum corneum tryptic enzyme
Presentation Aff - Purified
Reactivity Can, Hu, Rt
Applications WB
Clonality Polyclonal
Host Goat
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9Y337
Immunogen:
Peptide with sequence KAGRDSCQGD, from the internal region of the protein sequence
Genename:
25818
Antibody type Ab
Application Peptide ELISA: 1/4000.
Western Blot: 0.1-0.3 µg/ml.
Background Kallikrein 5 was originally described from the skin as an enzyme involved in turnover of the stratum corneum, and later cloned from human EST libraries as a Kallikrein like enzyme. The skin is known to contain trypsin like and chymotrypsin like proteinases of 32 kDa and 25 kDa respectively, and these were determined to be hK5 and hK7. Kallikrein 5 is found is greatest abundance in the skin, and also in the brain, with lesser signal in the kidney, lung, mammary gland, and testis. Human breast milk is reported to contain high levels of Kallikrein 5. Less stringent PCR detects hK5 in many tissues, and analysis of cell lines by Western blot shows that many cell lines make hK5.
Concentration 0.5 mg/ml
General Readings 1. Michael IP, Pampalakis G, Mikolajczyk SD, Malm J, Sotiropoulou G, Diamandis EP.
Human tissue kallikrein 5 is a member of a proteolytic cascade pathway involved in seminal clot liquefaction and potentially in prostate cancer progression. J Biol Chem. 2006 May 5;281(18):12743-50. Epub 2006 Mar 3.
PMID: 16517595
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity Chromatography.
Buffer System:
Tris saline, pH 7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer.
State:
Liquid purified Ig fraction.
Aff - Purified
Species Reactivity
Species reactivity (expected):
Rat and Canine.
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody recognizes KLK5.
Gene ID 25818
FocusOn and Reviews
FocusOns:
Targets

Accessory Products

Proteins and/or Positive Controls

Proteins for KLK5 / Kallikrein-5 (2 products)

Catalog No. Species Pres. Purity   Source  
H00025818-Q01-10

KLK5 / Kallikrein-5

KLK5 / Kallikrein-5 Human in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00025818-Q01-25

KLK5 / Kallikrein-5

KLK5 / Kallikrein-5 Human in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.

Positive controls for KLK5 / Kallikrein-5 (1 products)

Catalog No. Species Pres. Purity   Source  
H00025818-T01

KLK5 293T Cell Transient Overexpression Lysate(Denatured)

KLK5 293T Cell Transient Overexpression Lysate(Denatured)
0.1 ml / €240.00
  Abnova Taiwan Corp.