Product Description for Lamin-A/C (LMNA)
anti Lamin-A/C (LMNA).
Properties: Control Peptide
Presentation: Purified
Properties: Control Peptide
Presentation: Purified
Properties for Lamin-A/C (LMNA)
| Product Category | Antibodies |
|---|---|
| Quantity | 50 µg |
| Synonyms | 70 kDa Lamin, FocusOn028, FocusOn098, LMN1, LMNA, Lamin A, Lamin A + C, Lamin-A/C, NY-REN-32, NYREN32, Nuclear Envelope Marker, Renal carcinoma antigen NY-REN-32 |
| Presentation | Purified |
| Clonality | Polyclonal |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | Acris Antibodies GmbH |
| Material safety datasheet | MSDS for Polyclonal Antibodies (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Antibody type | Ab/CP |
| Application | Western blot: It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37°C. |
| Background | Nuclear Lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type Lamins and B-type Lamins. The A-type Lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. Lamin A, Lamin C and Lamin Adel 10, while the B-type Lamins include two proteins arising from two distinct genes, i.e. Lamin B1 and Lamin B2. Recent evidence has revealed that mutations in A-type Lamins give rise to a range of rare but dominant genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease and Dunnigan-type familial partial lipodystrophy. In addition, the expression of A-type Lamins coincides with cell differentiation and as A-type Lamins specifically interact with chromatin, a role in the regulation of differential gene expression has been suggested for A-type Lamins. |
| Concentration | 0.2 mg/ml |
| Storage | Store the antibody undiluted at -20°C or for long term storage (in aliquots) at -70°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Format |
|
| Specificity |
|
| Gene ID | 4000 |
| FocusOn and Reviews |
|
| Targets |
Accessory Products
Proteins and/or Positive Controls
Positive controls for Lamin-A/C (LMNA) (3 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00004000-T01 |
Lamin-A/C (LMNA) Lysate(Denatured) |
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 |
0.1 ml /
€240.00
|
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| Abnova Taiwan Corp. | |||||||
| NBL1-12564 |
Lamin A Lysate |
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![Western Blot: Lamin A Lysate [NBL1-12564] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for LMNA](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/Lamin A Lysate-Western Blot-NBL1-12564-img0001.jpg) |
0.1 mg /
€370.00
|
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| Novus Biologicals Inc. | |||||||
| NBL1-12565 |
Lamin A Lysate |
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|
0.1 mg /
€370.00
|
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| Novus Biologicals Inc. | |||||||
Recommended Secondary Antibodies for Lamin-A/C (LMNA) (0 products)
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