Product Description for Lamin-A/C (LMNA)
Rabbit anti Human, Mouse, Rat Lamin-A/C (LMNA).
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.
Properties for Lamin-A/C (LMNA)
| Product Category | Antibodies |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | 70 kDa Lamin, FocusOn028, FocusOn098, LMN1, LMNA, Lamin A, Lamin A + C, Lamin-A/C, NY-REN-32, NYREN32, Nuclear Envelope Marker, Renal carcinoma antigen NY-REN-32 |
| Presentation | Aff - Purified |
| Reactivity | Hu, Ms, Rt |
| Applications | P, WB |
| Clonality | Polyclonal |
| Host | Rabbit |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | Acris Antibodies GmbH |
Datasheet Extract
| Immunogen |
|
|---|---|
| Antibody type | Ab |
| Control peptide | AP00082CP-N |
| Add. information | Blocking peptide (AP00082CP-N) is available separately. |
| Application | Immunohistochemistry (15-20 µg/ml). Western blot analysis (0.5-4 µg/ml). |
| Background | Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control, DNA replication and chromatin organization. Lamin A is specifically cleaved by caspase-6 and therefore serves as a marker for caspase-6 activation. During apoptosis the 70 kDa lamin A is cleaved to a large (40-45 kDa) and small (23 kDa) fragment. The cleavage of lamins results in nuclear disregulation and cell death. |
| Concentration | 0.2 mg/ml |
| Storage | Store the antibody undiluted at -20°C or for long term storage (in aliquots) at -70°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Format |
|
| Specificity |
|
| Gene ID | 4000 |
| FocusOn and Reviews |
|
| Targets |
Accessory Products
Proteins and/or Positive Controls
Positive controls for Lamin-A/C (LMNA) (3 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00004000-T01 |
Lamin-A/C (LMNA) Lysate(Denatured) |
||||||
 |
0.1 ml /
€240.00
|
||||||
| Abnova Taiwan Corp. | |||||||
| NBL1-12564 |
Lamin A Lysate |
||||||
![Western Blot: Lamin A Lysate [NBL1-12564] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for LMNA](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/Lamin A Lysate-Western Blot-NBL1-12564-img0001.jpg) |
0.1 mg /
€370.00
|
||||||
| Novus Biologicals Inc. | |||||||
| NBL1-12565 |
Lamin A Lysate |
||||||
|
0.1 mg /
€370.00
|
||||||
| Novus Biologicals Inc. | |||||||
Recommended Secondary Antibodies for Lamin-A/C (LMNA) (6 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | TRITC | |||||
| Acris Antibodies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
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