Lamin-A/C (LMNA) - SM5157 | acris-antibodies.com

Product Description for Lamin-A/C (LMNA)

Mouse anti Bovine, Human, Porcine Lamin-A/C (LMNA) mab636.
Presentation: Supernatant
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for Lamin-A/C (LMNA)

Product Category	Antibodies
Quantity	0.2 ml
Synonyms	70 kDa Lamin, FocusOn028, FocusOn098, LMN1, LMNA, Lamin A, Lamin A + C, Lamin-A/C, NY-REN-32, NYREN32, Nuclear Envelope Marker, Renal carcinoma antigen NY-REN-32
Presentation	Supernatant
Reactivity	Bov, Hu, Por
Applications	C, ICC/IF, WB
Clonality	Monoclonal
Clone	mab636
Host	Mouse
Isotype	IgG2b
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	Acris Antibodies GmbH

Datasheet Extract

Immunogen	Swiss Prot Num: P02545 Immunogen: Porcine lamin preparation Genename: 4000
Antibody type	Ab
Add. information	SM5157 has been widely used for detection of lamin A/C control in siRNA experiments.
Application	Western Blot (1/100): detects ~ 70 and 65 kDa proteins corresponding to lamin A and C, respectively, from HeLa cell extract. Immunofluorescence (1/100). Immunohistochemistry on frozen sections (1/100).
Background	Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. These proteins are found in many different cell types in three different forms (A, B, and C). Lamins A and C are alternatively spliced versions of the LMNA gene. The LMNA gene has been linked to many disorders of the muscular system, nervous system, and the fat distributions systems including: Emery-Dreifuss muscular dystrophy, Dunnigan-type familial partial lipodystrophy (FPLD), limb-girdle muscular dystrophy (LGMD1B), dilated cardiomyopathy (CMD1A), axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1), and mandibuloacral dysplasia (MAD).
General Readings	Nature, 411:494-498, 2001. Exp. Cell Res., 190:185-194, 1990.
Storage	Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Format	State: Liquid tissue culture supernatant containing 0.05% sodium azide Supernatant
Specificity	Specificity: This antibody detects lamin A/C from human, bovine and porcine samples. Other species not tested.
Gene ID	4000
FocusOn and Reviews	FocusOns: Antibodies to Lamins - FocusOn 028
Targets	Lamin-A/C (LMNA) antibody

Accessory Products

Proteins and/or Positive Controls

Positive controls for Lamin-A/C (LMNA) (3 products)

Catalog No.	Species
H00004000-T01	Lamin-A/C (LMNA) Lysate(Denatured)
		0.1 ml / €240.00
		Abnova Taiwan Corp.
NBL1-12564	Lamin A Lysate
		0.1 mg / €370.00
		Novus Biologicals Inc.
NBL1-12565	Lamin A Lysate
		0.1 mg / €370.00
		Novus Biologicals Inc.

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