SP4366P LTB4R / BLTR antibody

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50 µg / €380.00
Please visit the appropriate website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human, Mouse, Rat LTB4R / BLTR

Product Description for LTB4R / BLTR

Rabbit anti Human, Mouse, Rat LTB4R / BLTR.
Presentation: Aff - Purified
Product is tested for Paraffin Sections.

Properties for LTB4R / BLTR

Product Category Primary Antibodies
Target Category
Quantity 50 µg
Synonyms BLT, BLT1, CMKRL1, Chemoattractant receptor-like 1, G-protein coupled receptor 16, GPR16, LTB4-R 1, Leukotriene B4 receptor 1, P2RY7, P2Y purinoceptor 7, P2Y7
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications P
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q15722
Immunogen:
Synthetic 16 amino acid peptide from 3rd Cytoplasmic domain of Human Leukotriene B4 ReceptorEpitope: Cytoplasmic Domain.
Genename:
1241
Remarks:
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Horse, Rabbit (100%); Bovine (88%); Opossum, Platypus (81%).
Control peptide SP4366CP
Application Immunohistochemistry on Paraffin Embedded Sections: 5-10 µg/ml. 
Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Background BLT1 is a Chemoattractant Receptor that binds the potent chemoattractant leukotriene B4 (LTB4) which is involved in defense against infection. Leukotriene B4 also activates the transcription factor PPAR alpha, resulting in the activation of genes that terminate inflammatory processes. Although BLT1 shows homology to other P2Y receptors, it does not function as a purinoreceptor.
Part of the coding regions of BLTR2 (LS57180) have been duplicated and are part of the 5' UTR noncoding regions of the clusters BLT1 (LS190955) and CIDE-B (LS54843) on chromosome 14.
BLTR1 has been reported in blood, bone marrow, brain, heart, liver, and skeletal muscle. In addition, BLTR1 has been shown to be highly expressed in leukocytes and lymphoid tissues such as spleen, thymus, and lymph node. ESTs have been isolated from B-cell/lung/testis, breast, colon, eye, kidney, skin, spleen, testis, and tonsil libraries.
Concentration 1.0 mg/ml
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Peptide Immunoaffinity Chromatography
Buffer System:
PBS, pH 7.7
Preservatives:
0.09% Sodium Azide
State:
Liquid purified Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human.
Specificity
Specificity:
Reacts with Leukotriene B4 Receptor BLTR1/P2Y7 (Family: GPCR, Subfamily: Chemoattractant). 
BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
Gene ID 1241
FocusOn and Reviews
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Accessory Products

Proteins and/or Positive Controls

Proteins for LTB4R / BLTR (1 products)

Catalog No. Species Pres. Purity   Source  
H00001241-G01

LTB4R / BLTR

LTB4R / BLTR Human
2 µg / €400.00
  Abnova Taiwan Corp.
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