SP4638P Leukotriene B4 receptor 1 (Cytopl. Dom.) antibody

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50 µg / €380.00
Delivery Time: 5-7 working days

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Rabbit anti Human, Mouse, Rat Leukotriene B4 receptor 1

Product Description for Leukotriene B4 receptor 1

Rabbit anti Human, Mouse, Rat Leukotriene B4 receptor 1.
Properties: (Cytopl. Dom.)
Presentation: Aff - Purified
Product is tested for Paraffin Sections.

Properties for Leukotriene B4 receptor 1

Product Category Antibodies
Quantity 50 µg
Synonyms BLT, BLT1, BLTR, CMKRL1, Chemoattractant receptor-like 1, FocusOn080, G-protein coupled receptor 16, GPR16, LTB4-R 1, LTB4R, P2RY7, P2Y purinoceptor 7, P2Y7, Review 006
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications P
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH

Datasheet Extract

Immunogen
Swiss Prot Num:
Q15722
Immunogen:
Synthetic 16 amino acid peptide from 2nd cytoplasmic domain of Human Leukotriene B4 Receptor. Epitope: Cytoplasmic Domain.
Genename:
1241
Remarks:
Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon (94%); Monkey, Marmoset (88%); Rat, Bovine (81%).
Property Cytopl. Dom.
Antibody type Ab
Application Immunohistochemistry on Paraffin Embedded Sections: 7-17 µg/ml. 
Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Background BLT1 is a Chemoattractant Receptor that binds the potent chemoattractant leukotriene B4 (LTB4) which is involved in defense against infection. Leukotriene B4 also activates the transcription factor PPAR alpha, resulting in the activation of genes that terminate inflammatory processes. Although BLT1 shows homology to other P2Y receptors, it does not function as a purinoreceptor.
BLTR1 has been reported in blood, bone marrow, brain, heart, liver, and skeletal muscle. In addition, BLTR1 has been shown to be highly expressed in leukocytes and lymphoid tissues such as spleen, thymus, and lymph node. ESTs have been isolated from B-cell/lung/testis, breast, colon, eye, kidney, skin, spleen, testis, and tonsil libraries.
Concentration 1.0 mg/ml
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Format
Purification:
Immunoaffinity Chromatography
Buffer System:
PBS
Preservatives:
0.09% Sodium Azide
State:
Liquid purified Ig fraction
Aff - Purified
Specificity
Specificity:
Recognizes Human Leukotriene B4 Receptor BLTR1 (Family: GPCR, Subfamily: Chemoattractant). 
BLAST analysis of the peptide immunogen showed no homology with other human proteins, except LTB4R2 (56%), ZNF644 (44%).
Species:
Human.
Gene ID 1241
FocusOn and Reviews
FocusOns:
Reviews:
Targets

Accessory Products

Proteins and/or Positive Controls

Proteins for Leukotriene B4 receptor 1 (1 products)

Catalog No. Species Pres. Purity   Source  
H00001241-G01

Leukotriene B4 receptor 1

Leukotriene B4 receptor 1 Human
2 µg / €400.00
  Abnova Taiwan Corp.