DM393 MMP-11 (active form) antibody

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1 ml / €520.00
Delivery Time: 5-7 working days

Quick Overview

Mouse anti Human MMP-11 SL3.05

Product Description for MMP-11

Mouse anti Human MMP-11 SL3.05.
Properties: (active form)
Presentation: Purified
Product is tested for Immunoprecipitation, Western blot / Immunoblot, Paraffin Sections.

Properties for MMP-11

Product Category Antibodies
Quantity 1 ml
Synonyms MMP11, Matrix metalloproteinase-11, Review 001, SL-3, ST3, STMY3, Stromelysin-3
Presentation Purified
Reactivity Hu
Applications IP, P, WB
Clonality Monoclonal
Clone SL3.05
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH

Datasheet Extract

Immunogen
Swiss Prot Num:
P24347
Immunogen:
BALB/C mice were immunized with a recombinant protein corresponding to active form of human MMP-11.
Genename:
4320
Property active form
Antibody type Ab
Application Immunoprecipitation.
Western Blot.
Immunohistochemistry on Paraffin Embedded Sections: Use a dilution of 1/50-1/100 in an ABC method (incubation time: 30 minutes at room temperature).
No special pretreatment is required.
Recommended Positive Control: Placenta.
Background Matrix metalloproteinase (MMPs) are a family of closely related zinc-containing proteolytic enzymes, capable of degrading connective tissue components. MMP-11 is localized on the long arm of chromosome 22. MMP-11 gene was originally identified on the basis that it is expressed specifically in stromal cells surrounding invasive breast carcinomas. MMP-11 is expression is found more specifically in malignant tumors than in benign ones.
General Readings
  • Basset et al. Crit Rev Oncol Hematol 26: 43, 1997.
  • Hahnel et al. Intl J Cancer 55: 771, 1993.
  • Muller et al. Virchows Arch 430: 213, 1997.
  • Thewes et al. Clin Exp Dermatol 24: 122, 1999.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
State:
Purified Ascites containing Sodium Azide as preservative.
Purified
Specificity
Specificity:
This antibody Reacts with a protein of 60 kD (latent), 47 kD (active) and 35 kD (degradation product).
Cellular Localization: Cytoplasmic.
Species:
Human.
Gene ID 4320
FocusOn and Reviews
Reviews:
Targets

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