NB110-60992 MMP-13 antibody

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0.1 mg / €430.00
Please visit the appropriate website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human MMP-13 MM0019-12E10

Product Description for MMP-13

Mouse anti Human MMP-13 MM0019-12E10.
Presentation: Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for MMP-13

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms Collagenase 3, MMP13, Matrix metalloproteinase-13
Presentation Purified
Reactivity Hu
Applications P, WB
Clonality Monoclonal
Clone MM0019-12E10
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P45452
Immunogen:
This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with purified human recombinant human MMP-13).
Genename:
4322
Antibody type Ab
Isotype control AM03095PU-N, SM10P (for use in human samples)
Application immunohistochemistry, Western Blot, This antibody recognizes human MMP-13 in western blot without cross reactivity with other human MMPs., immunohistochemistry 1:50-1:200, Western Blot 1:500-1:2000,
Background Collagenase 3 (MMP13) is a secreted 452 residue protein which is released from cells as aninactive zymogen and activated extracellularly by removal of its propeptide. MMP13 was first identified in tumor cells but has since been found in synoviocytes and normal fibroblasts stimulated by IL6 or a combination of TNF alpha and IL1. Under normal conditions, MMP13 is expressed during embryogenesis (fetal bone development) and is present only at very low levels in adult tissue. However, this enzyme is reported to be involved in the development and metastasis of breast and lung carcinomas, chondrosarcomas and osteosarcomas, head and neck carcinomas and some forms of skin cancer. Additionally, this enzyme plays an important role in degenerative bone diseases including osteoarthritis and rheumatoid arthritis. In rodents, MMP13 is thought to fill the role of MMP1, which they appear to lack.
Concentration 0.2 mg/ml
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
protein G purified
Buffer System:
No Preservative
Purity:
protein G purified
State:
Purified
Specificity
Specificity:
MMP13 (MM0019-12E10)
Species:
Human
Gene ID 4322
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Accessory Products

Proteins and/or Positive Controls

Proteins for MMP-13 (4 products)

Catalog No. Species Pres. Purity   Source  
AR51360PU-N

MMP-13 (His-tag)

MMP-13 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €730.00
  Acris Antibodies GmbH
AR51360PU-S

MMP-13 (His-tag)

MMP-13 Human Purified > 90 % by SDS - PAGE E. coli
20 µg / €300.00
  Acris Antibodies GmbH
H00004322-Q01-10

MMP-13

MMP-13 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00004322-Q01-25

MMP-13

MMP-13 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.

Positive controls for MMP-13 (2 products)

Catalog No. Species Pres. Purity   Source  
H00004322-T01

MMP13 293T Cell Transient Overexpression Lysate(Denatured)

MMP13 293T Cell Transient Overexpression Lysate(Denatured)
0.1 ml / €240.00
  Abnova Taiwan Corp.
NBL1-13152

MMP13 Lysate

Western Blot: MMP13 Lysate [NBL1-13152] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for MMP13
0.1 mg / €370.00
  Novus Biologicals Inc.
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