AP13171PU-N MMP-14 (N-term) antibody

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0.1 mg / €330.00
Delivery Time: 7-10 working days

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Rabbit anti Human MMP-14

AP13171PU-N

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  • AP13171PU-N

Product Description for MMP-14

Rabbit anti Human MMP-14.
Properties: (N-term)
Presentation: Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.

Properties for MMP-14

Product Category Antibodies
Quantity 0.1 mg
Synonyms MMP-X1, MMP14, Matrix metalloproteinase-14, Membrane-type-1 matrix metalloproteinase, Review 001
Presentation Purified
Reactivity Hu
Applications E, P, WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH

Datasheet Extract

Immunogen
Swiss Prot Num:
P50281
Immunogen:
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MMP14.
Genename:
4323
Property N-term
Antibody type Ab
Control peptide AP13171CP-N
Application ELISA: 1/1,000.
Western blotting: 1/100 - 1/500.
Immunohistochemistry: 1/50 - 1/100.
Background Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP14 seems to specifically activate progelatinase A, and may thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. Expression is significant in stromal cells of colon, breast, and head and neck.
Caution This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Concentration 0.25 mg/ml
General Readings
  • Will, H., et al., Eur. J. Biochem. 231(3):602-608 (1995).
  • Takino, T., et al., Gene 155(2):293-298 (1995).
  • Okada, A., et al., Proc. Natl. Acad. Sci. U.S.A. 92(7):2730-2734 (1995).
  • Sato, H., et al., Nature 370(6484):61-65 (1994).
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Buffer System:
PBS with 0.09% (W/V) sodium azide
State:
Liquid purified Ig
Purified
Specificity
Specificity:
This antibody reacts to MMP14.
Species:
Human.
Gene ID 4323
FocusOn and Reviews
Reviews:
Targets

Accessory Products

Proteins and/or Positive Controls

Proteins for MMP-14 (2 products)

Catalog No. Species Pres. Purity   Source  
AR05067PU-N

MMP-14

MMP-14 Human
5 µg / €490.00
  Acris Antibodies GmbH
H00004323-P01

MMP-14

MMP-14 Human Purified
2 µg / €250.00
  Abnova Taiwan Corp.

Positive controls for MMP-14 (1 products)

Catalog No. Species Pres. Purity   Source  
NBL1-13153

MMP14 Lysate

Western Blot: MMP14 Lysate [NBL1-13153] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for MMP14
0.1 mg / €370.00
  Novus Biologicals Inc.