Product Description for MMP-14
Rabbit anti Human, Mouse, Rat MMP-14.
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.
Properties for MMP-14
| Product Category | Antibodies |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | MMP-X1, MMP14, Matrix metalloproteinase-14, Membrane-type-1 matrix metalloproteinase, Review 001 |
| Presentation | Aff - Purified |
| Reactivity | Hu, Ms, Rt |
| Applications | P, WB |
| Clonality | Polyclonal |
| Host | Rabbit |
| Isotype | IgG |
| Shipping to | Not USA/Canada |
| PDF datasheet | View Datasheet |
| Manufacturer | Novus Biologicals Inc. |
Datasheet Extract
| Immunogen |
|
|---|---|
| Antibody type | Ab |
| Add. information | Research Areas: Cancer |
| Application | ELISA, immunohistochemistry, Western Blot, Western blot analysis of MMP-14 (P509) antibody in extracts from NIH/3T3 cells. Immunohistochemistry analysis of MMP-14 (P509) antibody in paraffin-embedded human breast carcinoma tissue., ELISA 1:5000-1:10000, Western Blot 1:500-1:1000, immunohistochemistry 1:50-1:200, |
| Background | The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-9 (also designated 92 kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase, fibroblast collagenase or collagenase-1), and cysteine proteases and may play a role in bone osteoclastic resorption. MMP-1 is downregulated by p53, and abnormality of p53 expression may contribute to joint degradation in rheumatoid arthritis by regulating MMP-1 expression. |
| Concentration | 1 mg/ml |
| Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Format |
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| Specificity |
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| Gene ID | 4323 |
| FocusOn and Reviews | |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for MMP-14 (2 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| AR05067PU-N |
MMP-14 |
||||||
 |
Human |
5 µg /
€490.00
|
|||||
| Acris Antibodies GmbH | |||||||
| H00004323-P01 |
MMP-14 |
||||||
|
Human | Purified |
2 µg /
€250.00
|
||||
| Abnova Taiwan Corp. | |||||||
Positive controls for MMP-14 (1 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| NBL1-13153 |
MMP14 Lysate |
||||||
![Western Blot: MMP14 Lysate [NBL1-13153] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for MMP14](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/MMP14 Lysate-Western Blot-NBL1-13153-img0001.jpg) |
0.1 mg /
€370.00
|
||||||
| Novus Biologicals Inc. | |||||||
Recommended Secondary Antibodies for MMP-14 (6 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | TRITC | |||||
| Acris Antibodies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
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