Product Description for MMP-23
Rabbit anti Human, Mouse, Rat MMP-23.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.
Properties for MMP-23
| Product Category | Antibodies |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | Femalysin, MIFR-1, MMP21, MMP22, MMP23A, MMP23B, Matrix metallopeptidase 21, Matrix metalloprotease 22, Matrix metalloproteinase-23, Review 001 |
| Presentation | Aff - Purified |
| Reactivity | Hu, Ms, Rt |
| Applications | WB |
| Clonality | Polyclonal |
| Host | Rabbit |
| Isotype | IgG |
| Shipping to | Not USA/Canada |
| PDF datasheet | View Datasheet |
| Manufacturer | Novus Biologicals Inc. |
Datasheet Extract
| Immunogen |
|
|---|---|
| Antibody type | Ab |
| Add. information | Research Areas: Cancer |
| Application | ELISA, Western Blot, Western blot analysis of MMP-23 (V371) antibody in extracts from SKOV3 cells., ELISA 1:10000-1:20000, Western Blot 1:500-1:1000, |
| Background | Matrix metalloproteinases (MMPs) are highly homologous Zn2+ endopeptidases involved in extracellular matrix breakdown. MMP mediated extracellular remodeling occurs in normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, including arthritis and metastasis. MMP-23 exhibits sequence similarity with most MMPs, but displays a difference in domain structure. The MMP-23 protein contains prepro-, catalytic, cysteine-rich, Interleukin-1 receptor-related and proline-rich domains. Lacking a recognizable signal sequence, MMP-23 has a short prodomain. In addition, MMP-23 contains a single cysteine residue that can be part of the cysteine-switch mechanism operation for maintaining enzyme latency. MMP-23 is a membrane-anchored glycoprotein with type II topology. Subcellular localization is predominantly perinuclear. A dramatic switch in MMP-23 mRNA localization from granulosa cells to theca-externa/ fibroblasts and ovarian surface epithelium occurs during follicular development. MMP-23 is expressed in ovary, testis and prostate, suggesting that MMP-23 plays a specialized role in the reproductive processes. The human MMP-23 gene maps to chromosome 1p36.3 |
| Concentration | 1 mg/ml |
| Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Format |
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| Specificity |
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| Gene ID | 8510 |
| FocusOn and Reviews | |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for MMP-23 (3 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00008510-P01 |
MMP-23 (MMP23B) |
||||||
 |
Human | Purified |
2 µg /
€250.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00008510-Q01-10 |
MMP-23 |
||||||
|
Human | in vitro transl. |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00008510-Q01-25 |
MMP-23 |
||||||
|
Human | in vitro transl. |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
Positive controls for MMP-23 (1 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| NBL1-13157 |
MMP23B Lysate |
||||||
![Western Blot: MMP23B Lysate [NBL1-13157] - Western Blot experiments. Left-Control; Right -Over-expression Lysate for MMP23B.](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/MMP23B Lysate-Western Blot-NBL1-13157-img0001.jpg) |
0.1 mg /
€370.00
|
||||||
| Novus Biologicals Inc. | |||||||
Recommended Secondary Antibodies for MMP-23 (6 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | TRITC | |||||
| Acris Antibodies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
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