Product Description for MMP-3
Mouse anti Human MMP-3 F36P1B4.
Presentation: Aff - Purified
Product is tested for Frozen Sections, Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.
Presentation: Aff - Purified
Product is tested for Frozen Sections, Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.
Properties for MMP-3
| Product Category | Antibodies |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | MMP3, Matrix metalloproteinase-3, Review 001, SL-1, STMY1, Stromelysin-1, Transin-1 |
| Presentation | Aff - Purified |
| Reactivity | Hu |
| Applications | C, E, P, WB |
| Clonality | Monoclonal |
| Clone | F36P1B4 |
| Host | Mouse |
| Isotype | IgG1 |
| Shipping to | Not USA/Canada |
| PDF datasheet | View Datasheet |
| Manufacturer | Novus Biologicals Inc. |
Datasheet Extract
| Immunogen |
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|---|---|
| Antibody type | Ab |
| Add. information | Research Areas: Cancer |
| Application | ELISA, immunohistochemistry, Western Blot, Each lot of this antibody is quality control tested by Western blotting. For Western blotting, suggested working dilution(s): Use 5-10 mug per 5 ml antibody dilution buffer for each mini-gel. Immunohistochemistry. It is recommended that the reagent be titrated for optimal performance for each application., ELISA immunohistochemistry Western Blot |
| Background | Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that degrade substances within the extracellular matrix. The MMP family includes six different groups of enzymes: collagenases, gelatinases, stromelysins, transmembrane MMPs, matrilysins and others. MMPs are secreted as proenzymes that have to be cleaved in order to be activated. Other MMPs, plasmins as well as other factors activate MMPs. MMPs are thought to play an important role in tissue remodeling associated with various physiological and pathological processes. MMP3 degrades fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase. MMP3 is thought to play a prominent role in the pathogenesis of rheumatoid arthritis. Clone F36P1B4 has been shown to be useful for western blotting, ELISA and immunohistochemistry of human MMP3. |
| General Readings |
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| Storage | Store at 4C. Do not freeze. |
| Format |
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| Specificity |
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| Gene ID | 4314 |
| FocusOn and Reviews | |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for MMP-3 (7 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| AR09439PU-N |
MMP-3 |
||||||
 |
Human | > 98 % | E. coli |
10 µg /
€230.00
|
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| Acris Antibodies GmbH | |||||||
| AR09439PU-S |
MMP-3 |
||||||
|
Human | > 98 % | E. coli |
2 µg /
€130.00
|
|||
| Acris Antibodies GmbH | |||||||
| PA1265X |
MMP-3 |
||||||
|
Human | Purified | > 98 % | E. coli |
Regular Price: 20 µg / €170.00 Special Price: 20 µg / €119.00 |
||
| Acris Antibodies GmbH | |||||||
| H00004314-P01-10 |
MMP-3 |
||||||
|
Human | Purified |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00004314-P01-25 |
MMP-3 |
||||||
|
Human | Purified |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00004314-Q01-10 |
MMP-3 |
||||||
|
Human | in vitro transl. |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00004314-Q01-25 |
MMP-3 |
||||||
|
Human | in vitro transl. |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
Positive controls for MMP-3 (2 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00004314-T01 |
MMP3 293T Cell Transient Overexpression Lysate(Denatured) |
||||||
|
0.1 ml /
€240.00
|
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| Abnova Taiwan Corp. | |||||||
| NBL1-13159 |
MMP3 Lysate |
||||||
![Western Blot: MMP3 Lysate [NBL1-13159] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for MMP3](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/MMP3 Lysate-Western Blot-NBL1-13159-img0001.jpg) |
0.1 mg /
€370.00
|
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| Novus Biologicals Inc. | |||||||
Recommended Secondary Antibodies for MMP-3 (8 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1253AP |
Mouse IgG (H+L chain) antibody |
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|
|
Rabbit | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1253B |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1253F |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1253HRP |
Mouse IgG (H+L chain) antibody |
||||||
|
Rabbit | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1253TR |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Texas Red | |||||
| Acris Antibodies GmbH | |||||||
| R1403R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Rabbit | PE | |||||
| Acris Antibodies GmbH | |||||||
| R1405R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Goat | PE | |||||
| Acris Antibodies GmbH | |||||||
| R1455R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
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