NB100-1651 P2RX1 / P2X1 antibody

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50 µl / €280.00
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Quick Overview

Rabbit anti Rat P2RX1 / P2X1

Product Description for P2RX1 / P2X1

Rabbit anti Rat P2RX1 / P2X1.
Presentation: Serum
Product is tested for Paraffin Sections.

Properties for P2RX1 / P2X1

Product Category Antibodies
Quantity 50 µl
Synonyms ATP receptor, P2X purinoceptor, Purinergic receptor
Presentation Serum
Reactivity Rt
Applications P
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P47824
Immunogen:
Synthetic peptide (GLQENMRTS), corresponding to amino acids 364-372 of Rat P2X1.
Genename:
25505
Antibody type Ab
Application Immunocytochemistry, immunohistochemistry, Immunohistochemistry-Frozen, Immunocytochemistry, Immunohistochemistry-Frozen, Optimal dilutions and concentrations should be determined by the end user., immunohistochemistry 1:1000, Immunocytochemistry 1:1000, Immunohistochemistry-Frozen 1:1000
Background The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.
General Readings General / background references:Vulchanova L et al. Differential distribution of two ATP-gated channels (P2X receptors) determined by immunocytochemistry. Proc Natl Acad Sci U S A 93:8063-7 (1996). PubMed PMID: 8755603
Valera S et al. A new class of ligand-gated ion channel defined by P2x receptor for extracellular ATP. Nature 371:516-9 (1994). PubMed PMID: 7523951
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
Whole antisera
Buffer System:
0.05% Sodium Azide
Purity:
Whole antisera
State:
Serum
Specificity
Specificity:
P2X1
Species:
Rat
Gene ID 25505
FocusOn and Reviews
Reviews:
Targets

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