AP06000PU-N pan Actin antibody

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0.1 mg / €320.00
Delivery Time: 10 working days

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Rabbit anti Human, Mouse, Rat pan Actin

AP06000PU-N

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  • AP06000PU-N

Product Description for pan Actin

Rabbit anti Human, Mouse, Rat pan Actin.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot, Paraffin Sections.

Properties for pan Actin

Product Category Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications E, P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH

Datasheet Extract

Antibody type Ab
Immunogen
Application ELISA: 1/10000-1/20000.
Western Blot: 1/500-1/1000.
Immunohistochemistry on Paraffin Sections: 150-1/200.
Background All eukaryotic cells express Actin, which often constitutes as much as 50% of total cellular protein. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. While lower eukaryotes, such as yeast, have only one Actin gene, higher eukaryotes have several isoforms encoded by a family of genes. At least six types of Actin are present in mammalian tissues and fall into three classes. Alpha Actin expression is limited to various types of muscle, whereas beta and gamma are the principle constituents of filaments in other tissues. Members of the small GTPase family regulate the organization of the Actin cytoskeleton. Rho controls the assembly of Actin stress fibers and focal adhesion, Rac regulates Actin filament accumulation at the plasma membrane and Cdc42 stimulates formation of filopodia.
Concentration 1.0 mg/ml
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity Chromatography using epitope-specific immunogen
Buffer System:
PBS, pH~7.2
Preservatives:
15 mM Sodium azide
State:
Liquid purified Ig fraction (>95% pure by SDS-PAGE)
Aff - Purified
Specificity
Specificity:
This antibody detects endogenous levels of pan Actin (region surrounding Glu361).
Species:
Human, Mouse, Rat.
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