Product Description for Progesterone receptor
Rabbit anti Human Progesterone receptor BV7.
Presentation: Supernatant
Product is tested for Paraffin Sections.
Presentation: Supernatant
Product is tested for Paraffin Sections.
Properties for Progesterone receptor
| Product Category | Antibodies |
|---|---|
| Quantity | 0.5 ml |
| Synonyms | FocusOn049, NR3C3, Nuclear Receptor Subfamily 3 Group C Member 3, PGR, PR |
| Presentation | Supernatant |
| Reactivity | Hu |
| Applications | P |
| Clonality | Monoclonal |
| Clone | BV7 |
| Host | Rabbit |
| Isotype | IgG |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | Acris Antibodies GmbH |
Datasheet Extract
| Immunogen |
|
|---|---|
| Antibody type | Ab |
| Add. information | Cellular Localization: Nuclear |
| Application | Immunohistochemistry on paraffin sections (1:25 to 1:100 in an ABC method), requires high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining; incubation period of 30-60 minutes at room temperature. Positive control: Breast carcinoma. |
| Background | The progesterone receptor is an intracellular steroid receptor that specifically binds progesterone. Expressed by a single gene (chromosome 11q22), it has two main forms, A and B, that differ in their molecular weight. It has been proposed that expression of PR determination indicates a responsive estrogen receptor (ER) pathway, and therefore, may predict likely response to endocrine therapy in human breast cancer. A number of studies have shown that PR determination provides supplementary information to ER, in predicting response to endocrine therapy as well as estimating survival. PR has proved superior to ER as a prognostic indicator in some studies. |
| General Readings |
|
| Storage | Store the antibody at 2 - 8 °C. Shelf life: one year from despatch. |
| Format |
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| Specificity |
|
| Gene ID | 5241 |
| FocusOn and Reviews | |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for Progesterone receptor (2 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00005241-Q01-10 |
Progesterone receptor |
||||||
 |
Human | in vitro transl. |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00005241-Q01-25 |
Progesterone receptor |
||||||
|
Human | in vitro transl. |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
Recommended Secondary Antibodies for Progesterone receptor (6 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | TRITC | |||||
| Acris Antibodies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
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