RGS19

Product Description for RGS19

Rabbit anti Human, Mouse, Rat RGS19.
Presentation: Serum
Product is tested for Frozen Sections, Paraffin Sections, Western blot / Immunoblot.

Properties for RGS19

Product Category	Antibodies
Quantity	0.15 ml
Synonyms	FocusOn111, G-alpha-interacting protein, GAIP, GNAI3IP, Regulator of G-protein signaling 19
Presentation	Serum
Reactivity	Hu, Ms, Rt
Applications	C, P, WB
Clonality	Polyclonal
Host	Rabbit
Shipping to	Not USA/Canada
PDF datasheet	View Datasheet
Manufacturer	Novus Biologicals Inc.

Datasheet Extract

Immunogen	Swiss Prot Num: P49795 Immunogen: A synthetic peptide as a part of human, rat, mouse Regulator of G-protein signaling 19 (RGS19, G-alpha-interacting protein, GAIP, GNAI3IP,RGSGAIP) conjugated to an immunogenic carrier protein has been used as the immunogen. Genename: 10287
Antibody type	Ab
Add. information	Reconstitute in 0.15 ml of sterile water. Centrifuge to remove any insoluble material. When reconstituting, glycerol (1:1) may be added for an additional stability.
Application	immunohistochemistry, Western Blot, Immunohistochemistry and Western Blot , immunohistochemistry , Western Blot 1:300 to 1:2000
Background	G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G-protein signaling) family and specifically interacts with G protein, GAI3. This protein is a guanosine triphosphatase-activating protein that functions to down-regulate Galpha i/Galpha q-linked signaling. Alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.; FUNCTION: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein. SUBCELLULAR LOCATION: Membrane; Lipid-anchor. TISSUE SPECIFICITY: Highest expression in lung. Placenta, liver and heart also express high levels of GAIP.
General Readings	de Vries L, et al. Proc. Natl. Acad. Sci. U.S.A. 92:11916-11920(1995). Deloukas P, et al. Nature 414:865-871(2001). de Vries L, et al. Proc. Natl. Acad. Sci. U.S.A. 93:15203-15208(1996). de Alba E, et al. J. Mol. Biol. 291:927-939(1999). Wang J, et al. J. Biol. Chem. 273:26014-26025(1998). Ogier-Denis E, et al. J. Biol. Chem. 275:39090-39095(2000).
Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format	Purification: Whole antisera Buffer System: No Preservative Purity: Whole antisera State: Serum
Specificity	Specificity: RGS19. Species: Human, Mouse, Rat
Gene ID	10287
FocusOn and Reviews	FocusOns: Regulators of G-Protein Signaling - FocusOn 111
Targets	RGS19 antibody

Accessory Products

Proteins and/or Positive Controls

Proteins for RGS19 (8 products)

Catalog No.	Species	Pres.	Purity	Source
AR09750PU-L	RGS19 (1-217, His-tag)
	Human	Purified	> 90 %	E. coli	0.5 mg / €750.00
					Acris Antibodies GmbH
AR09750PU-N	RGS19 (1-217, His-tag)
	Human	Purified	> 90 %	E. coli	0.1 mg / €300.00
					Acris Antibodies GmbH
NBP1-50894-0.1	RGS19
	Human	Purified			0.1 mg / €340.00
					Novus Biologicals Inc.
NBP1-50894-0.5	RGS19
	Human	Purified			0.5 mg / €740.00
					Novus Biologicals Inc.
H00010287-P01-10	RGS19
	Human			in vitro transl.	10 µg / €350.00
					Abnova Taiwan Corp.
H00010287-P01-25	RGS19
	Human			in vitro transl.	25 µg / €500.00
					Abnova Taiwan Corp.
H00010287-Q01-10	RGS19
	Human			in vitro transl.	10 µg / €350.00
					Abnova Taiwan Corp.
H00010287-Q01-25	RGS19
	Human			in vitro transl.	25 µg / €500.00
					Abnova Taiwan Corp.

Positive controls for RGS19 (2 products)

Catalog No.	Species
NBL1-15325	RGS19 Lysate
		0.1 mg / €370.00
		Novus Biologicals Inc.
NBL1-15326	RGS19 Lysate
		0.1 mg / €370.00
		Novus Biologicals Inc.

Recommended Secondary Antibodies for RGS19 (6 products)

Catalog No.	Host	Pres.
R1364AP	Rabbit IgG (H+L chain) antibody
	Goat	AP
			Acris Antibodies GmbH
R1364B	Rabbit IgG (H+L chain) antibody
	Goat	Biotin
			Acris Antibodies GmbH
R1364F	Rabbit IgG (H+L chain) antibody
	Goat	FITC
			Acris Antibodies GmbH
R1364HRP	Rabbit IgG (H+L chain) antibody
	Goat	HRP
			Acris Antibodies GmbH
R1364T	Rabbit IgG (H+L chain) antibody
	Goat	TRITC
			Acris Antibodies GmbH
R1427R	Rabbit IgG F(ab)2 Fragment (H+L chain) antibody
	Donkey	PE
			Acris Antibodies GmbH