SP2091P S100A1 (S100A/B) antibody

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1 ml / €310.00
Delivery Time: 3-5 working days

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Rabbit anti Bovine, Human, Mouse, Rat S100A1

Product Description for S100A1

Rabbit anti Bovine, Human, Mouse, Rat S100A1.
Properties: (S100A/B)
Presentation: Purified
Product is tested for Frozen Sections, Paraffin Sections.

Properties for S100A1

Product Category Antibodies
Quantity 1 ml
Synonyms FocusOn041, S-100 protein alpha chain, S-100 protein subunit alpha, S100 alpha, S100 calcium-binding protein A1, S100-A1, S100A
Presentation Purified
Reactivity Bov, Hu, Ms, Rt
Applications C, P
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P02639
Immunogen:
Bovine brain S-100
Genename:
528735
Property S100A/B
Antibody type Ab
Application Immunohistochemistry on Frozen Sections: 1/10-1/40.
Immunohistochemistry on Paraffin Sections: 1/10-1/40.
This product does not require protein digestion pretreatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.
Recommended Positive Control: Brain, skin or Human melanoma.
Background Among tumours of the human central and peripheral nervous systems, schwannomas, ependymomas and astrogliomas of different stages, including glioblastomas show positive reactions. S100 can be detected in almost all benign naevi and malignant melanocytic tumours of the skin, and in Langerhans cells in the skin.
General Readings
  • Moore BW. A soluble protein characteristic of the nervous system. Biochem Biophys Res Commun. 1965 Jun 9;19(6):739-44. PubMed PMID: 4953930.
  • Kindblom LG, Lodding P, Rosengren L, Baudier J, Haglid K. S-100 protein in melanocytic tumors. An immunohistochemical investigation of benign and malignant melanocytic tumors and metastases of malignant melanoma and a characterization of the antigen in comparison to human brain. Acta Pathol Microbiol Immunol Scand A. 1984 Jul;92(4):219-30. PubMed PMID: 6496075.
  • Lauriola L, Michetti F, Sentinelli S, Cocchia D. Detection of S-100 labelled cells in nasopharyngeal carcinoma. J Clin Pathol. 1984 Nov;37(11):1235-8. PubMed PMID: 6389603.
  • Lam TT, Kwong JM, Tso MO. Early glial responses after acute elevated intraocular pressure in rats. Invest Ophthalmol Vis Sci. 2003 Feb;44(2):638-45. PubMed PMID: 12556393.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Ammonium Sulphate Precipitation
Buffer System:
PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer.
State:
Liquid IgG fraction
Purified
Specificity
Specificity:
This antibody reacts with S-100 A and S-100 B.
This protein is present in brain glial cells and in ependymal cells.
This antibody also stains Schwann cells of the peripheral nervous system.
Species:
Bovine, Human, Mouse and Rat.
Gene ID 528735
FocusOn and Reviews
FocusOns:
Targets

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