AP02347PU-S STAT5 / STAT5A pTyr694 antibody

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50 µg / €240.00
Please visit the appropriate website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse STAT5 / STAT5A

AP02347PU-S

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  • AP02347PU-S

Product Description for STAT5 / STAT5A

Rabbit anti Human, Mouse STAT5 / STAT5A.
Properties: pTyr694
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Properties for STAT5 / STAT5A

Product Category Antibodies
Target Category
Quantity 50 µg
Synonyms MGF, Mammary gland factor, STAT-5, STAT-5A, Signal transducer and activator of transcription 5A
Presentation Aff - Purified
Reactivity Hu, Ms
Applications P, WB
Clonality Polyclonal
Host Rabbit
Molecular weight 90 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P42229
Immunogen:
Synthesized phosphopeptide derived from Human STAT5A around the phosphorylation site of Tyrosine 694 (D-G-Yp-V-K).
Genename:
6776
Property pTyr694
Antibody type Ab
Application Western blot: 1/500-1/1000. 
Immunohistochemistry on Paraffin Sections: 1/50-1/100.
Background The STAT proteins serve as both cytoplasmic signal transducers and nuclear activators of transcription. STATs are mediators involved in cytokine signalling. In response to a specific cytokine signal, STAT proteins are phosphorylated on conserved tyrosine residues. Phosphorylated STAT proteins dimerize via their SH2 domains and move to the nucleus. The STAT dimers bind to specific DNA elements resulting in transcriptional regulation of downstream target genes. STAT5 is activated in response to prolactine, growth hormone, GM-CSF, and IL-2.
Concentration 1.0 mg/ml
General Readings
  1. Gouilleux F, et al. (1994) EMBO J. 13: 4361-4369.
  2. Dentelli P, et al. (1999) J Immunol. 163: 2151-2159.
  3. Meinke A, et al. (1996) Mol Cell Biol. 16: 6937-6944.
Storage Store the antibody (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: One year from despatch.
Format
Purification:
Immunoaffinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Buffer System:
PBS (without Mg2+ and Ca2+), pH 7.4, 150 M NaCl
Preservatives:
0.02% Sodium Azide
Stabilizers:
50% Glycerol
State:
Liquid purified Ig fraction
Aff - Purified
Specificity
Specificity:
This antibody detects endogenous levels of STAT5A only when phosphorylated at Tyrosine 694.
Species:
Human, Mouse and Rat.
Gene ID 6776
FocusOn and Reviews
Reviews:

Accessory Products

Proteins and/or Positive Controls

Proteins for STAT5 / STAT5A (7 products)

Catalog No. Species Pres. Purity   Source  
GTX28003

STAT5 / STAT5A

STAT5 / STAT5A n/a
0.1 mg / €230.00
  GeneTex Inc.
H00006776-P01-10

STAT5 / STAT5A

STAT5 / STAT5A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €350.00
  Abnova Taiwan Corp.
H00006776-P01-25

STAT5 / STAT5A

STAT5 / STAT5A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €500.00
  Abnova Taiwan Corp.
H00006776-Q01-10

STAT5 / STAT5A

STAT5 / STAT5A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00006776-Q01-25

STAT5 / STAT5A

STAT5 / STAT5A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.
P1426

STAT5 / STAT5A

STAT5 / STAT5A Human
0.1 mg / €240.00
  Abnova Taiwan Corp.
P1427

STAT5 / STAT5A

STAT5 / STAT5A Human
0.1 mg / €240.00
  Abnova Taiwan Corp.

Positive controls for STAT5 / STAT5A (2 products)

Catalog No. Species Pres. Purity   Source  
H00006776-T01

STAT5A 293T Cell Transient Overexpression Lysate(Denatured)

STAT5A 293T Cell Transient Overexpression Lysate(Denatured)
0.1 ml / €240.00
  Abnova Taiwan Corp.
NBL1-16528

STAT5A Lysate

Western Blot: STAT5A Lysate [NBL1-16528] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for STAT5A
0.1 mg / €370.00
  Novus Biologicals Inc.
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