ARP39001_P050 STAT5B antibody

See related secondary antibodies

Search for all "STAT5B"

50 µg / €330.00
Please visit the appropriate website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Bovine, Chicken, Human, Mouse, Porcine, Rat, Zebrafish STAT5B

ARP39001_P050

More Views

  • ARP39001_P050
  • ARP39001_P050

Product Description for STAT5B

Rabbit anti Bovine, Chicken, Human, Mouse, Porcine, Rat, Zebrafish STAT5B.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Properties for STAT5B

Product Category Antibodies
Target Category
Quantity 50 µg
Synonyms STAT-5B, Signal transducer and activator of transcription 5B
Presentation Aff - Purified
Reactivity Bov, Chk, Hu, Ms, Por, Rt, Ze
Applications P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer AVIVA Systems Biology

Datasheet Extract

Immunogen
Swiss Prot Num:
P51692
Immunogen:
Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human STAT5B with an internal ID of S04610
Genename:
6777
Antibody type Ab
Add. information Rabbit Ig G is purified by peptide affinity chromatography method. 90kDa
Application Suggested dilution at 1 ?g/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. ELISA titre using peptide based assay: 1:312500
Background STAT5B is a member of the STAT family of transcription factors. In response to cytokines andgrowth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5B mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
General Readings Mohankumar,K.M., (2008) Endocrinology 149 (5), 2219-2229
Storage Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20DegC. Avoid repeat freeze-thaw cycles.
Format
Purification:
Rabbit Ig G is purified by peptide affinity chromatography method.
Buffer System:
Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20DegC. Avoid repeat freeze-thaw cycles.
State:
Aff - Purified
Specificity
Species:
Human,Mouse,Rat
Gene ID 6777
FocusOn and Reviews
Reviews:

Accessory Products

Proteins and/or Positive Controls

Proteins for STAT5B (4 products)

Catalog No. Species Pres. Purity   Source  
H00006777-P01-10

STAT5B

STAT5B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00006777-P01-25

STAT5B

STAT5B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.
H00006777-Q01-10

STAT5B

STAT5B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00006777-Q01-25

STAT5B

STAT5B Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.

Positive controls for STAT5B (1 products)

Catalog No. Species Pres. Purity   Source  
H00006777-T01

STAT5B 293T Cell Transient Overexpression Lysate(Denatured)

STAT5B 293T Cell Transient Overexpression Lysate(Denatured)
0.1 ml / €240.00
  Abnova Taiwan Corp.
  • Pinterest
  • LinkedIn