SM5062 TER ATPase / VCP antibody

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0.1 ml / €370.00
Delivery Time: 7-10 working days

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Mouse anti Human, Mouse, Rat TER ATPase / VCP 5

SM5062

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Product Description for TER ATPase / VCP

Mouse anti Human, Mouse, Rat TER ATPase / VCP 5.
Presentation: Ascites
Product is tested for Immunocytochemistry/Immunofluorescence, Flow Cytometry, Frozen Sections, Immunoprecipitation, Western blot / Immunoblot, Paraffin Sections.

Properties for TER ATPase / VCP

Product Category Antibodies
Quantity 0.1 ml
Synonyms 15S Mg(2+)-ATPase p97 subunit, Review 012, Transitional endoplasmic reticulum ATPase, Valosin-containing protein
Presentation Ascites
Reactivity Hu, Ms, Rt
Applications C, F, ICC/IF, IP, P, WB
Clonality Monoclonal
Clone 5
Host Mouse
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P55072
Immunogen:
Synthetic Peptide: C G(792) G S V Y T E D N D D D L Y G (806) corresponding to amino acid residues 792-806 from Mouse VCP.
Genename:
7415
Remarks:
This peptide (SM5062CP) is available for use in Neutralization and Control experiments.
Antibody type Ab
Control peptide SM5062CP
Application Flow Cytometry: 1/400.
Immunoprecipitation.

Immunofluorescence: 1000.  
Western Blot: 1/2000, detects an ~97 kDa protein representing VCP from total lysate of cultured Human B cells. 
Immunohistochemistry on Frozen Sections: 1/500.
Immunohistochemistry on Paraffin Embedded Sections:
 1/500.
Background Valosin-containing protein (VCP or p97) belongs to the AAA (ATPase associated activities) family and acts as a molecular chaperone to a wide variety of cellular activities. Some of these activities include the alteration of both nuclear and mitotic golgi membranes, ubiquitin-proteasome dependent protein degradation, regulation of the NF-kappa b pathway, and extraction of membrane proteins.
VCP has been shown to contain a substrate binding domain (N) and two conserved ATPase domains (D1 and D2). The three dimensional structure of VCP resembles that of a cylinder with the D1 and D2 stacked upon one another in a homo-hexameric ring formation.
General Readings
  • J. Biol. Chem., Jun 2006; 281: 17369-17378.
  • JBC 2006 manuscript, M600509200v1. 
  • J Immunol. 2007 Feb 15;178(4):2535-41. 
  • Autophagy. 2010 Feb;6(2):217-27. 
  • Reprod Biol Endocrinol. 2011 Aug 19;9():117. 
  • Muscle Nerve. 2007 Oct;36(4):447-54.
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Preservatives:
0.05% Sodium Azide
State:
Liquid ascites
Ascites
Specificity
Specificity:
This antibody detects VCP protein in Human, Mouse, and Rat samples.
Gene ID 7415
FocusOn and Reviews
Reviews:
Targets

Accessory Products

Proteins and/or Positive Controls

Proteins for TER ATPase / VCP (10 products)

Catalog No. Species Pres. Purity   Source  
H00007415-P01-10

TER ATPase / VCP

TER ATPase / VCP Human Purified
10 µg / €350.00
  Abnova Taiwan Corp.
H00007415-P01-25

TER ATPase / VCP

TER ATPase / VCP Human Purified
25 µg / €500.00
  Abnova Taiwan Corp.
H00007415-P02

TER ATPase / VCP

TER ATPase / VCP Human Purified
10 µg / €420.00
  Abnova Taiwan Corp.
H00007415-P02-10

TER ATPase / VCP

TER ATPase / VCP Human Purified
10 µg / €350.00
  Abnova Taiwan Corp.
H00007415-P02-25

TER ATPase / VCP

TER ATPase / VCP Human Purified
25 µg / €500.00
  Abnova Taiwan Corp.
H00007415-Q01-10

TER ATPase / VCP

TER ATPase / VCP Human Purified
10 µg / €350.00
  Abnova Taiwan Corp.
H00007415-Q01-25

TER ATPase / VCP

TER ATPase / VCP Human Purified
25 µg / €500.00
  Abnova Taiwan Corp.
H00007415-Q02

TER ATPase / VCP

TER ATPase / VCP Human Purified
10 µg / €330.00
  Abnova Taiwan Corp.
H00007415-Q02-10

TER ATPase / VCP

TER ATPase / VCP Human Purified
10 µg / €350.00
  Abnova Taiwan Corp.
H00007415-Q02-25

TER ATPase / VCP

TER ATPase / VCP Human Purified
25 µg / €500.00
  Abnova Taiwan Corp.

Positive controls for TER ATPase / VCP (1 products)

Catalog No. Species Pres. Purity   Source  
NBL1-17707

p97/VCP Lysate

Western Blot: p97/VCP Lysate [NBL1-17707] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for VCP
0.1 mg / €370.00
  Novus Biologicals Inc.