SM7103F TLR5 (700-800) antibody

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0.1 mg / €370.00
Please visit the appropriate website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Canine, Human, Mouse TLR5 19D759.2

Product Description for TLR5

Mouse anti Canine, Human, Mouse TLR5 19D759.2.
Properties: (700-800)
Presentation: FITC
Product is tested for Flow Cytometry.

Properties for TLR5

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms TIL3, Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3
Presentation FITC
Reactivity Can, Hu, Ms
Applications F
Clonality Monoclonal
Clone 19D759.2
Host Mouse
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O60602
Immunogen:
KLH-conjugated synthetic peptide corresponding to a portion of human TLR5 between amino acids 700-800
Genename:
7100
Property 700-800
Antibody type Ab
Application Flow cytometry (Cell surface).
Flow cytometry (Intracellular): 0.5-1.0 µg/10e6 cells.
Background The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs characterized so far activate the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway. Thirteen homologs of TLRs (TLR1-13) have been described. Toll-like receptor 5 (TLR5) expression is upregulated following exposure to bacteria or to the TLR5 agonist, flagellin. Gram-negative bacteria, stimulate monocyte/macrophage cells in a TLR5-specific, CD14-independent manner. The TLR5 receptor thus appears to be the principal means by which the innate immune system recognizes flagellated bacterial pathogens.
Concentration 0.5 mg/ml
General Readings
  1. Muzio M, Natoli G, Saccani S, Levrero M, and Mantovani A.J. Exp. Med. 187: 2097-2101 (1998).
  2. Medzhitov R and Janeway CA. Cell 91: 295-298 (1997).
  3. Chuang TH and Ulevitch RJ. Biochim. Biophys. Acta 1518 (1-2): 157-161 (2001).
Storage Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf life: six months from despatch.
Format
Label:
FITC
Purification:
Protein G chromatography
Buffer System:
10 mM Tris, 150 mM NaCl, containing 0.05% sodium azide
State:
Liquid Ig fraction
Species Reactivity
Species reactivity (expected):
Dog
Species reactivity (tested):
Human, mouse
Specificity
Specificity:
This antibody recognizes an intracellular epitope in the cytoplasmic domain of TLR5.

Accessory Products

Proteins and/or Positive Controls

Proteins for TLR5 (4 products)

Catalog No. Species Pres. Purity   Source  
H00007100-Q01-10

TLR5

TLR5 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00007100-Q01-25

TLR5

TLR5 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.
H00007100-Q03-10

TLR5

TLR5 Human 12.5% SDS-PAGE Stained with Coomassie Blue
10 µg / €350.00
  Abnova Taiwan Corp.
H00007100-Q03-25

TLR5

TLR5 Human 12.5% SDS-PAGE Stained with Coomassie Blue
25 µg / €500.00
  Abnova Taiwan Corp.

Positive controls for TLR5 (1 products)

Catalog No. Species Pres. Purity   Source  
NBL1-16954

TLR5 Lysate

Western Blot: TLR5 Lysate [NBL1-16954] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for TLR5
0.1 mg / €520.00
  Novus Biologicals Inc.
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