DM3507 VEGFR-1 / Flt-1 antibody

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0.1 mg / €320.00
Please visit the appropriate website of Acris Antibodies or contact your local Distributor to buy this product.

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Mouse anti Human VEGFR-1 / Flt-1 FLTEWI (EWI)

DM3507

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  • DM3507

Product Description for VEGFR-1 / Flt-1

Mouse anti Human VEGFR-1 / Flt-1 FLTEWI (EWI).
Presentation: Purified
Product is tested for Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Western blot / Immunoblot.

Properties for VEGFR-1 / Flt-1

Product Category Antibodies
Quantity 0.1 mg
Synonyms FLT, FLT1, FRT, Fms-like tyrosine kinase 1, FocusOn005, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, VEGF Receptor 1, VEGFR1, Vascular endothelial growth factor receptor 1, Vascular permeability factor receptor
Presentation Purified
Reactivity Hu
Applications E, ICC/IF, IP, WB
Clonality Monoclonal
Clone FLTEWI (EWI)
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH

Datasheet Extract

Immunogen
Swiss Prot Num:
P17948
Immunogen:
Recombinant Human soluble extracellular Flt-1 (D1-D5)
Genename:
2321
Antibody type Ab
Application ELISA (1-10 µg/ml).
Western blotting (1-10 µg/ml).
Immunoprecipitation (1-5 µg/ml lysate or reaction volume).
Immunofluorescence.
Background VEGF Receptor 1 (also known as FLT) belongs to the src gene family and shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The protein acts as a receptor for VEGF, VEGFB and PGF. An alternatively spliced form of the gene produces a soluble protein (sFlt1) which binds vascular endothelial growth factor (VEGF) with high affinity. sFlt1 has a higher affinity for VEGF indicating that it may function as an inhibitor in the VEGF response. VEGF Receptor 1 is specifically expressed in most vascular endothelial cells and peripheral blood monocytes. VEGF and its high-affinity binding receptors, the tyrosine kinases FLK1 and FLT1, are thought to be important for the development of embryonic vasculature. It has been shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity. Because sFLT1 has a higher affinity for VEGF than does FLK1, it may function as an inhibitor of VEGF response.
Storage

Prior to reconstitution store at 2-8°C.
Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Format
Purification:
Protein G purified
Buffer System:
PBS
State:
Lyophilized purified IgG fraction
Purified
Reconstitution:
Restore in sterile water to a concentration of 0.1-1.0 mg/ml
Specificity
Specificity:
The monoclonal antibody will recognize recombinant and naturally occurring form of Human VEGFR-1/Flt-1.
It cross reacts with Mouse Flt-1 (e.g. natural occurring soluble Mouse Flt-1) in Western blot analysis (Figure 1).
Gene ID 2321
FocusOn and Reviews
FocusOns:
Targets

Accessory Products

Proteins and/or Positive Controls

Proteins for VEGFR-1 / Flt-1 (14 products)

Catalog No. Species Pres. Purity   Source  
AR00181PU-N

VEGFR-1 / Flt-1 (His-tagged), Active Enzyme

VEGFR-1 / Flt-1 Human Purified > 70 % SF9 cells
10 µg / €300.00
  Acris Antibodies GmbH
DA3532

VEGFR-1 / Flt-1

VEGFR-1 / Flt-1 Human Purified > 85 % Insect cells
5 µg / €160.00
  Acris Antibodies GmbH
DA3532X

VEGFR-1 / Flt-1

VEGFR-1 / Flt-1 Human Purified > 85 % Insect cells
20 µg / €240.00
  Acris Antibodies GmbH
DA3533

VEGFR-1 / Flt-1 (D1-D4)

VEGFR-1 / Flt-1 Human Purified > 60 % Insect cells
5 µg / €170.00
  Acris Antibodies GmbH
DA3533X

VEGFR-1 / Flt-1 (D1-D4)

VEGFR-1 / Flt-1 Human Purified > 60 % Insect cells
20 µg / €280.00
  Acris Antibodies GmbH
DA3534

VEGFR-1 / Flt-1 (Fc Chimera)

VEGFR-1 / Flt-1 Human Purified > 95 % Insect cells
10 µg / €150.00
  Acris Antibodies GmbH
DA3534X

VEGFR-1 / Flt-1 (Fc Chimera)

VEGFR-1 / Flt-1 Human Purified > 95 % Insect cells
50 µg / €270.00
  Acris Antibodies GmbH
DA3539

VEGFR-1 / Flt-1 (D1-D5)

VEGFR-1 / Flt-1 Human Purified > 90 % Insect cells
5 µg / €160.00
  Acris Antibodies GmbH
DA3539X

VEGFR-1 / Flt-1 (D1-D5)

VEGFR-1 / Flt-1 Human Purified > 90 % Insect cells
20 µg / €240.00
  Acris Antibodies GmbH
DA3541

VEGFR-1 / Flt-1 (D1-D3)

VEGFR-1 / Flt-1 Human Purified > 90 % Insect cells
5 µg / €170.00
  Acris Antibodies GmbH
DA3541X

VEGFR-1 / Flt-1 (D1-D3)

VEGFR-1 / Flt-1 Human Purified > 90 % Insect cells
20 µg / €280.00
  Acris Antibodies GmbH
NBP1-94701

VEGFR-1 / Flt-1

VEGFR-1 / Flt-1 Human Purified
10 µg / €390.00
  Novus Biologicals Inc.
H00002321-Q01-10

VEGFR-1 / Flt-1

VEGFR-1 / Flt-1 Human in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00002321-Q01-25

VEGFR-1 / Flt-1

VEGFR-1 / Flt-1 Human in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.

Positive controls for VEGFR-1 / Flt-1 (2 products)

Catalog No. Species Pres. Purity   Source  
H00002321-T01

FLT1 293T Cell Transient Overexpression Lysate(Denatured)

FLT1 293T Cell Transient Overexpression Lysate(Denatured)
0.1 ml / €240.00
  Abnova Taiwan Corp.
NBL1-06699

VEGF Receptor 1 Lysate

Western Blot: VEGFR1 Antibody [NB100-527] - Western Blot on VEGFR1 (A) empty vector control and (B) overexpression lysates [NBL1-06699].
0.1 ml / €170.00
  Novus Biologicals Inc.